Milli-Mark® Anti-PKCα-FITC Antibody, clone M4 | EMD Millipore FCMAB420F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark® Anti-PKCα-FITC Antibody, clone M4

catalog :

FCMAB420F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

reactivity :

domestic rabbit

application :

flow cytometry

product information

Catalog Number :

FCMAB420F

Subcategory :

Cell Signaling

Product Name :

Milli-Mark® Anti-PKCα-FITC Antibody, clone M4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10102

Host Name :

Mouse

Antigen :

PKCα-FITC

Clone :

Conjugate :

FITC

Isotype :

IgG1

Product Description :

Milli-Mark® Anti-PKCα-FITC Antibody, clone M4

Cross Reactivity :

Human;Rabbit

Background :

Protein Kinase c alpha (PKC alpha) is a 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell-cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide-dependent kinase-1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy-terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.

ALT Names :

aging-associated gene 6;protein kinase C alpha type;protein kinase C, alpha

Immunogen :

PKCα purified from rabbit brain cytosol.

Specificity :

Antibody recognizes PKCα.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.