Milli-Mark™ Anti-CAR-PE Antibody, clone RmcB | EMD Millipore FCMAB418PE product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CAR-PE Antibody, clone RmcB

catalog :

FCMAB418PE

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

RmcB

reactivity :

human, mouse

application :

flow cytometry

citations: 25

Reference
Lenman A, Liaci A, Liu Y, Årdahl C, Rajan A, Nilsson E, et al. Human adenovirus 52 uses sialic acid-containing glycoproteins and the coxsackie and adenovirus receptor for binding to target cells. PLoS Pathog. 2015;11:e1004657 pubmed publisher
Zhan Y, Yu B, Wang Z, Zhang Y, Zhang H, Wu H, et al. A fiber-modified adenovirus co-expressing HSV-TK and Coli.NTR enhances antitumor activities in breast cancer cells. Int J Clin Exp Pathol. 2014;7:2850-60 pubmed
Kaliberov S, Kaliberova L, Buggio M, Tremblay J, Shoemaker C, Curiel D. Adenoviral targeting using genetically incorporated camelid single variable domains. Lab Invest. 2014;94:893-905 pubmed publisher
Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton P, et al. Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting. J Biol Chem. 2014;289:680-95 pubmed publisher
Zhang X, Zheng Z, Shu B, Liu X, Zhang Z, Liu Y, et al. Human astrocytic cells support persistent coxsackievirus B3 infection. J Virol. 2013;87:12407-21 pubmed publisher
Markel D, Lam E, Harste G, Darr S, Ramke M, Heim A. Type dependent patterns of human adenovirus persistence in human T-lymphocyte cell lines. J Med Virol. 2014;86:785-94 pubmed publisher
Parker A, White K, Lavery C, Custers J, Waddington S, Baker A. Pseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction. Gene Ther. 2013;20:1158-64 pubmed publisher
Janssen J, Liu J, Skokan J, Gonçalves M, de Vries A. Development of an AdEasy-based system to produce first- and second-generation adenoviral vectors with tropism for CAR- or CD46-positive cells. J Gene Med. 2013;15:1-11 pubmed publisher
Yanagawa Matsuda A, Kitamura T, Higashino F, Yamano S, Totsuka Y, Shindoh M. E1A expression might be controlled by miR-214 in cells with low adenovirus productivity. Virus Res. 2012;170:85-90 pubmed publisher
Teigler J, Iampietro M, Barouch D. Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys. J Virol. 2012;86:9590-8 pubmed publisher
Kolawole A, Sharma P, Yan R, Lewis K, Xu Z, Hostetler H, et al. The PDZ1 and PDZ3 domains of MAGI-1 regulate the eight-exon isoform of the coxsackievirus and adenovirus receptor. J Virol. 2012;86:9244-54 pubmed publisher
Murphy A, Besmer D, Moerdyk Schauwecker M, Moestl N, Ornelles D, Mukherjee P, et al. Vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma. J Virol. 2012;86:3073-87 pubmed publisher
Yoon J, Jekle A, Najafi R, Ruado F, Zuck M, KHOSROVI B, et al. Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis. Antiviral Res. 2011;92:470-8 pubmed publisher
Borovjagin A, Dong J, Passineau M, Ren C, Lamani E, Mamaeva O, et al. Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cells. PLoS ONE. 2011;6:e24281 pubmed publisher
Adamson R, Frazier A, Evans H, Chambers K, Schenk E, Essand M, et al. In vitro primary cell culture as a physiologically relevant method for preclinical testing of human oncolytic adenovirus. Hum Gene Ther. 2012;23:218-30 pubmed publisher
Renois F, Hong S, Le Naour R, Gafa V, Talmud D, Andreoletti L, et al. Development of a recombinant CHO cell model for the investigation of CAR and DAF role during early steps of echovirus 6 infection. Virus Res. 2011;158:46-54 pubmed publisher
Lewis T, Glasgow J, Glandon A, Curiel D, Standaert D. Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy. PLoS ONE. 2010;5: pubmed publisher
Botta G, Perruolo G, Libertini S, Cassese A, Abagnale A, Beguinot F, et al. PED/PEA-15 modulates coxsackievirus-adenovirus receptor expression and adenoviral infectivity via ERK-mediated signals in glioma cells. Hum Gene Ther. 2010;21:1067-76 pubmed publisher
Liu X, Li J, Tian Y, Xu P, Chen X, Xie K, et al. Enhanced pancreatic cancer gene therapy by combination of adenoviral vector expressing c-erb-B2 (Her-2/neu)-targeted immunotoxin with a replication-competent adenovirus or etoposide. Hum Gene Ther. 2010;21:157-70 pubmed publisher
Sandberg L, Papareddy P, Silver J, Bergh A, Mei Y. Replication-competent Ad11p vector (RCAd11p) efficiently transduces and replicates in hormone-refractory metastatic prostate cancer cells. Hum Gene Ther. 2009;20:361-73 pubmed publisher
Vigl B, Zgraggen C, Rehman N, Banziger Tobler N, Detmar M, Halin C. Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro. Exp Cell Res. 2009;315:336-47 pubmed publisher
Nilsson E, Jamshidi F, Johansson S, Oberste M, Arnberg N. Sialic acid is a cellular receptor for coxsackievirus A24 variant, an emerging virus with pandemic potential. J Virol. 2008;82:3061-8 pubmed publisher
Satoh M, Wang H, Ishidoya S, Abe H, Moriya T, Hamada H, et al. Oncolytic virotherapy for prostate cancer by E1A, E1B mutant adenovirus. Urology. 2007;70:1243-8 pubmed
Hakkarainen T, Sarkioja M, Lehenkari P, Miettinen S, Ylikomi T, Suuronen R, et al. Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors. Hum Gene Ther. 2007;18:627-41 pubmed
Reimer D, Steppan I, Wiedemair A, Concin N, Hofstetter G, Marth C, et al. Soluble isoforms but not the transmembrane form of coxsackie-adenovirus receptor are of clinical relevance in epithelial ovarian cancer. Int J Cancer. 2007;120:2568-75 pubmed

product information

Catalog Number :

FCMAB418PE

Subcategory :

Cell Structure

Product Name :

Milli-Mark™ Anti-CAR-PE Antibody, clone RmcB

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P78310

Host Name :

Mouse

Antigen :

CAR-PE

Clone :

RmcB

Conjugate :

Phycoerythrin

Isotype :

IgG1

Product Description :

Milli-Mark™ Anti-CAR-PE Antibody, clone RmcB

Cross Reactivity :

Human

Background :

The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR's biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation.

ALT Names :

46 kD coxsackievirus and adenovirus receptor (CAR) protein;CVB3 binding protein;CVB3-binding protein;Coxsackievirus B-adenovirus receptor;coxsackie virus B receptor;coxsackie virus and adenovirus receptor

Immunogen :

Native human coxsackie virus-adenovirus receptor protein

Specificity :

Antibody recognizes CAR.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.