This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Milli-Mark™ Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4
catalog :
FCMAB389F
quantity :
100 tests
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
HUTS-4

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry, other
citations: 33
Published Application/Species/Sample/DilutionReference
  • other; mouse; 1:250; loading ...; fig 2a
Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher
Pan L, North H, Sahni V, Jeong S, McGuire T, Berns E, et al. ?1-Integrin and integrin linked kinase regulate astrocytic differentiation of neural stem cells. PLoS ONE. 2014;9:e104335 pubmed publisher
Lee S, Cheng H, Yuan Y, Wu S. Regulation of ionizing radiation-induced adhesion of breast cancer cells to fibronectin by alpha5beta1 integrin. Radiat Res. 2014;181:650-8 pubmed publisher
Lee S, Kim J, Cho S, Kim H, Shin H, Jeon J, et al. TIMP-1 modulates chemotaxis of human neural stem cells through CD63 and integrin signalling. Biochem J. 2014;459:565-76 pubmed publisher
Itokazu Y, Pagano R, Schroeder A, O Grady S, Limper A, Marks D. Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased ?1-integrin signaling and delayed wound repair. Am J Physiol Cell Physiol. 2014;306:C819-30 pubmed publisher
Lim H, Couchman J. Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. Biochim Biophys Acta. 2014;1840:2482-90 pubmed publisher
Bi J, Wang R, Zhang Y, Han X, Ampah K, Liu W, et al. Identification of nucleolin as a lipid-raft-dependent ?1-integrin-interacting protein in A375 cell migration. Mol Cells. 2013;36:507-17 pubmed publisher
Fu X, Xu M, Liu J, Qi Y, Li S, Wang H. Regulation of migratory activity of human keratinocytes by topography of multiscale collagen-containing nanofibrous matrices. Biomaterials. 2014;35:1496-506 pubmed publisher
Cheng H, Lee S, Wu S. Effects of N-acetyl-L-cysteine on adhesive strength between breast cancer cell and extracellular matrix proteins after ionizing radiation. Life Sci. 2013;93:798-803 pubmed publisher
Vickers D, Chory E, Harless M, Murthy S. p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay. PLoS ONE. 2013;8:e65828 pubmed publisher
Wang R, Bi J, Ampah K, Zhang C, Li Z, Jiao Y, et al. Lipid raft regulates the initial spreading of melanoma A375 cells by modulating ?1 integrin clustering. Int J Biochem Cell Biol. 2013;45:1679-89 pubmed publisher
Wilk C, Schildberg F, Lauterbach M, Cadeddu R, Fröbel J, Westphal V, et al. The tissue inhibitor of metalloproteinases-1 improves migration and adhesion of hematopoietic stem and progenitor cells. Exp Hematol. 2013;41:823-831.e2 pubmed publisher
Chiang Y, Ho K, Sun C, Chiu J, Lee F, Liao F, et al. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE. 2013;8:e61761 pubmed publisher
Abbonante V, Gruppi C, Rubel D, Gross O, Moratti R, Balduini A. Discoidin domain receptor 1 protein is a novel modulator of megakaryocyte-collagen interactions. J Biol Chem. 2013;288:16738-46 pubmed publisher
Zimmerman C, Austin P, Khong A, McLeod S, Bean B, Forestieri R, et al. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. Exp Cell Res. 2013;319:908-17 pubmed publisher
Srikanth M, Das S, Berns E, Kim J, Stupp S, Kessler J. Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition. Neuro Oncol. 2013;15:319-29 pubmed publisher
Yao H, Duan M, Yang L, Buch S. Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of ?1 integrins. FASEB J. 2013;27:1532-48 pubmed publisher
Madera L, Hancock R. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin. J Innate Immun. 2012;4:553-68 pubmed publisher
Xia H, Seeman J, Hong J, Hergert P, Bodem V, Jessurun J, et al. Low ?(2)?(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the ?-catenin pathway. Am J Pathol. 2012;181:222-33 pubmed publisher
Lippert D, Wilkins J. Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes. BMC Immunol. 2012;13:21 pubmed
Lei W, Xing S, Deng C, Ju X, Jiang X, Luo Z. Laminin/?1 integrin signal triggers axon formation by promoting microtubule assembly and stabilization. Cell Res. 2012;22:954-72 pubmed publisher
Wan S, Lin C, Lu Y, Lei H, Anderson R, Lin Y. Endothelial cell surface expression of protein disulfide isomerase activates ?1 and ?3 integrins and facilitates dengue virus infection. J Cell Biochem. 2012;113:1681-91 pubmed publisher
Zou L, Cao S, Kang N, Huebert R, Shah V. Fibronectin induces endothelial cell migration through ?1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766. J Biol Chem. 2012;287:7190-202 pubmed publisher
Huang C, Fu X, Liu J, Qi Y, Li S, Wang H. The involvement of integrin ?1 signaling in the migration and myofibroblastic differentiation of skin fibroblasts on anisotropic collagen-containing nanofibers. Biomaterials. 2012;33:1791-800 pubmed publisher
van de Vijver E, De Cuyper I, Gerrits A, Verhoeven A, Seeger K, Gutierrez L, et al. Defects in Glanzmann thrombasthenia and LAD-III (LAD-1/v) syndrome: the role of integrin ?1 and ?3 in platelet adhesion to collagen. Blood. 2012;119:583-6 pubmed publisher
Das M, Ithychanda S, Qin J, Plow E. Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils. PLoS ONE. 2011;6:e26355 pubmed publisher
Augoff K, Das M, Bialkowska K, McCue B, Plow E, Sossey Alaoui K. miR-31 is a broad regulator of ?1-integrin expression and function in cancer cells. Mol Cancer Res. 2011;9:1500-8 pubmed publisher
Quast T, Eppler F, Semmling V, Schild C, Homsi Y, Levy S, et al. CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration. Blood. 2011;118:1818-27 pubmed publisher
Liu X, Yan Z, Huang L, Guo M, Zhang Z, Guo C. Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-?1/focal adhesion kinase/c-Src signaling pathway. Oncol Rep. 2011;25:1343-51 pubmed publisher
Ohsawa K, Irino Y, Sanagi T, Nakamura Y, Suzuki E, Inoue K, et al. P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP. Glia. 2010;58:790-801 pubmed publisher
Chigaev A, Waller A, Amit O, Halip L, Bologa C, Sklar L. Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. J Biol Chem. 2009;284:14337-46 pubmed publisher
Ithychanda S, Das M, Ma Y, Ding K, Wang X, Gupta S, et al. Migfilin, a molecular switch in regulation of integrin activation. J Biol Chem. 2009;284:4713-22 pubmed publisher
product information
Catalog Number :
FCMAB389F
Subcategory :
Cell Structure
Product Name :
Milli-Mark™ Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P05556
Host Name :
Mouse
Antigen :
Integrin β1-FITC
Clone :
HUTS-4
Conjugate :
FITC
Isotype :
IgG2b
Product Description :
Milli-Mark™ Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4
Cross Reactivity :
Human
Background :
Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits 1 to 6 (CD49a to CD49f) also known as Very Late Antigens (VLA). CD29 is also called platelet GPIIa. The antigen mediates cellular adhesion and has broad cellular reactivity, but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes and on a minority of B lymphocytes. The "inducer" subpopulation of CD4+ lymphocytes co-express CD4 and CD29.
ALT Names :
Ligand-induced Binding Site;LIBS;CLIBS
Immunogen :
Generated against human beta1 integrins purified from Triton X-100 lysates of human lung, liver, and skeletal muscle tissues.
Specificity :
Antibody recognizes Integrin β1.
Package Size :
100 tests
Uses :
Flow Cytometry
Storage :
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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