Milli-Mark™ Anti-PP2A-PE Antibody, C subunit, clone 1D6 | EMD Millipore FCMAB336PE product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-PP2A-PE Antibody, C subunit, clone 1D6

catalog :

FCMAB336PE

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

1D6

The same clone is also sold as:

Santa Cruz Biotechnology: sc-80665

reactivity :

human, mouse, bovine

application :

flow cytometry

product information

Catalog Number :

FCMAB336PE

Subcategory :

Cell Signaling

Product Name :

Milli-Mark™ Anti-PP2A-PE Antibody, C subunit, clone 1D6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P67775

Host Name :

Mouse

Antigen :

PP2A-PE

Clone :

1D6

Conjugate :

Phycoerythrin

Isotype :

IgG2bκ

Product Description :

Milli-Mark™ Anti-PP2A-PE Antibody, C subunit, clone 1D6

Cross Reactivity :

Human

Background :

Type 2 protein serine/threonine phosphatase (PP2A) is a trimer composed of a catalytic C subunit and two regulatory (A and B) subunits; many isoforms for the A and B subunits have been found. PP2A has a high specific activity against the α subunit of phosphorylase kinase and is insensitive to Inhibitor-2. PP2A is distinguishable from PP2B/Calcineurin and PP2C by its partial activity in the absence of divalent cations, and by its high sensitivity to inhibition by okadaic acid. It is also thought to be the principal downmodulator of serine/threonine kinase cascades. PP2B requires Ca2+/calmodulin for activity, and is an activator of NFAT transcription factors. PP2C requires Mg2+, but is insensitive to okadaic acid, microcystin LR, or the calmodulin inhibitor trifluoperazine.

ALT Names :

Replication protein C;protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform;protein phosphatase 2, catalytic subunit, alpha isoform;serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform

Immunogen :

A synthetic peptide corresponding to amino acids 295-309 of the 36 kDa catalytic subunit of human protein phosphatase 2A (PP2A).

Specificity :

This antibody recognizes PP2A catalytic subunit.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.