Milli-Mark™ Anti-Vesicular Glutamate Transporter 1-PE Antibody, clone 3C10.2 | EMD Millipore FCMAB335PE product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-Vesicular Glutamate Transporter 1-PE Antibody, clone 3C10.2

catalog :

FCMAB335PE

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3C10.2

reactivity :

rat

application :

flow cytometry

product information

Catalog Number :

FCMAB335PE

Subcategory :

Neuroscience

Product Name :

Milli-Mark™ Anti-Vesicular Glutamate Transporter 1-PE Antibody, clone 3C10.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q62634

Host Name :

Mouse

Antigen :

Vesicular Glutamate Transporter 1-PE

Clone :

3C10.2

Conjugate :

Phycoerythrin

Isotype :

IgG1

Product Description :

Milli-Mark™ Anti-Vesicular Glutamate Transporter 1-PE Antibody, clone 3C10.2

Cross Reactivity :

Rat

Background :

VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate. Vesicular glutamate transporters pack the neurotransmitter into synaptic vesicles so that they can be released into the synapse. VGLUTs are dependent on a proton gradient that they create by hydrolysing adenosine triphosphate (ATP). VGLUTs have only between one hundredth and one thousandth the affinity for glutamate that EAATs have.

ALT Names :

VGluT1;Solute carrier family 17 member 7;Brain-specific Na(+)-dependent inorganic phosphate cotransporter

Immunogen :

Recombinant protein from rat Vesicular Glutamate Transporter-1

Specificity :

Antibody recognizes VGLUT-1.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.