Milli-Mark™ Anti-β-Tubulin-FITC Antibody, clone AA2 | EMD Millipore FCMAB321F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-β-Tubulin-FITC Antibody, clone AA2

catalog :

FCMAB321F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

AA2

The same clone is also sold as:

Santa Cruz Biotechnology: sc-80011
MilliporeSigma: T8328

reactivity :

human, mouse, bovine

application :

flow cytometry

product information

Catalog Number :

FCMAB321F

Subcategory :

Cell Structure

Product Name :

Milli-Mark™ Anti-β-Tubulin-FITC Antibody, clone AA2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P07437

Host Name :

Mouse

Antigen :

β-Tubulin-FITC

Clone :

AA2

Conjugate :

FITC

Isotype :

IgG1

Product Description :

Milli-Mark™ Anti-β-Tubulin-FITC Antibody, clone AA2

Cross Reactivity :

Human;Mouse;Rat;Bovine

Background :

Microtubules are constituent parts of the mitotic apparatus, cilia, flagella, and elements of the cytoskeleton. They consist principally of 2 soluble proteins, alpha- and beta-tubulin, each about 55 kDa in size. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is post-translationally modified . Beta tubulin influences the stability of the heterdimer, determined by whether the molecule of GTP bound to the beta tubulin subunit hydrolyzes to GDP along the microtubule protofilament. Beta tubulin has also been a target for various antitubulin agents used in the treatment of cancer. Studies have concluded that beta tubulin mutatons can contribute to drug resistance and may play a role in resistance to chemotherapy.

ALT Names :

Tubulin beta-5 chain;beta 5-tubulin;beta Ib tubulin;beta-4 tubulin;tubulin beta polypeptide;tubulin beta-1 chain;tubulin, beta;tubulin, beta polypeptide

Immunogen :

Purified bovine brain tubulin. The epitope recognized by this antibody has been mapped to amino acids 412-430.

Specificity :

Antibody recognizes Human beta tubulin

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.