Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2 | EMD Millipore FCMAB313PE product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2

catalog :

FCMAB313PE

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

10C2

The same clone is also sold as:

Abnova: MAB16239, MAB16290, MAB2332
Novus Biologicals: NBP2-80869, NB300-266
OriGene: TA309763, AM05803PU-M, TA320427
Invitrogen: 14-9843-95, MA1-110-A488, MA1-110-A647, MA5-16102, 14-9843-80, 41-9843-80, MA5-16105, MA5-16103, MA5-16104, 53-9843-82, MA1-110-A555, MA5-16106, MA1-110, 53-9843-80, 14-9843-37, 14-9843-82
BioLegend: 656804, 656806, 656812, 656805, 656808, 656802, 656801, 656811, 656810
Bio-Rad: OBT1610
Abcam: ab22035
Stemcell Technologies: 60091AD.1
LifeSpan Biosciences: LS-C142113, LS-B7877, LS-C142112, LS-C179723, LS-C142111, LS-B7181, LS-C142115, LS-C45602
Santa Cruz Biotechnology: sc-23927, sc-23927 AC
GeneTex: GTX30671

reactivity :

human, mouse

application :

flow cytometry

citations: 37

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig st1	Vishnyakova P, Volodina M, Tarasova N, Marey M, Tsvirkun D, Vavina O, et al. Mitochondrial role in adaptive response to stress conditions in preeclampsia. Sci Rep. 2016;6:32410 pubmed publisher
	Lee C, Zhan Q, Lezcano C, Frank M, Huang J, Larson A, et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest. 2014;94:1382-95 pubmed publisher
	Leite C, Silva N, Mendes S, Ribeiro A, de Faria J, LourenÃ§o T, et al. Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage. PLoS ONE. 2014;9:e111059 pubmed publisher
	Hwang D, Shin H, Kwon M, Choi J, Ryu B, Kim B. Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling. J Neurosci. 2014;34:12788-800 pubmed publisher
	Gervois P, Struys T, Hilkens P, Bronckaers A, Ratajczak J, Politis C, et al. Neurogenic maturation of human dental pulp stem cells following neurosphere generation induces morphological and electrophysiological characteristics of functional neurons. Stem Cells Dev. 2015;24:296-311 pubmed publisher
	Kawai H, Satomi K, Morishita Y, Murata Y, Sugano M, Nakano N, et al. Developmental markers of ganglion cells in the enteric nervous system and their application for evaluation of Hirschsprung disease. Pathol Int. 2014;64:432-42 pubmed publisher
	Baker G, Yadav V, Motsch S, Koschmann C, Calinescu A, Mineharu Y, et al. Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy. Neoplasia. 2014;16:543-61 pubmed publisher
	Kim H, Choi S, Yang W, Kim D, Lee D, Cho S, et al. PSA-NCAM(+) neural precursor cells from human embryonic stem cells promote neural tissue integrity and behavioral performance in a rat stroke model. Stem Cell Rev. 2014;10:761-71 pubmed publisher
	Nakahara A, Yoshida T, Yazawa M, Ehara T, Nakayama J, Kakita A, et al. "Gliomatosis encephali" as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli. Neuropathology. 2014;34:295-303 pubmed publisher
	Jelen S, Parm Ulhøi B, Larsen A, Frøkiær J, Nielsen S, Rutzler M. AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes. PLoS ONE. 2013;8:e75764 pubmed publisher
	Tonthat C, Di Girolamo N. Nestin expression in pterygia: potential role in angiogenesis. Br J Ophthalmol. 2014;98:801-7 pubmed publisher
	Wen D, Wang H, Heng B, Liu H. Increased expression of nestin in human pterygial epithelium. Int J Ophthalmol. 2013;6:259-63 pubmed publisher
	Stimpfel M, Skutella T, Cvjeticanin B, Meznaric M, Dovc P, Novakovic S, et al. Isolation, characterization and differentiation of cells expressing pluripotent/multipotent markers from adult human ovaries. Cell Tissue Res. 2013;354:593-607 pubmed publisher
	Skalli O, Wilhelmsson U, Orndahl C, Fekete B, Malmgren K, Rydenhag B, et al. Astrocytoma grade IV (glioblastoma multiforme) displays 3 subtypes with unique expression profiles of intermediate filament proteins. Hum Pathol. 2013;44:2081-8 pubmed publisher
	Lustremant C, Habeler W, Plancheron A, Goureau O, Grenot L, de la Grange P, et al. Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis. Cell Reprogram. 2013;15:233-46 pubmed publisher
	Jarzabek M, Huszthy P, Skaftnesmo K, McCormack E, Dicker P, Prehn J, et al. In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme. Mol Imaging. 2013;12:161-72 pubmed
	Lim J, Koh S, Olby N, Piedrahita J, Mariani C. Isolation and characterization of neural progenitor cells from adult canine brains. Am J Vet Res. 2012;73:1963-8 pubmed publisher
	Pai S, Verrier F, Sun H, Hu H, Ferrie A, Eshraghi A, et al. Dynamic mass redistribution assay decodes differentiation of a neural progenitor stem cell. J Biomol Screen. 2012;17:1180-91 pubmed
	Vasuri F, Fittipaldi S, Buzzi M, Degiovanni A, Stella A, D Errico Grigioni A, et al. Nestin and WT1 expression in small-sized vasa vasorum from human normal arteries. Histol Histopathol. 2012;27:1195-202 pubmed publisher
	Ceafalan L, Gherghiceanu M, Popescu L, Simionescu O. Telocytes in human skin--are they involved in skin regeneration?. J Cell Mol Med. 2012;16:1405-20 pubmed publisher
	Stimpfel M, Skutella T, Kubista M, Malicev E, Conrad S, Virant Klun I. Potential stemness of frozen-thawed testicular biopsies without sperm in infertile men included into the in vitro fertilization programme. J Biomed Biotechnol. 2012;2012:291038 pubmed publisher
	Zambo I, Hermanova M, Adamkova Krakorova D, Mudry P, Zitterbart K, Kyr M, et al. Nestin expression in high-grade osteosarcomas and its clinical significance. Oncol Rep. 2012;27:1592-8 pubmed publisher
	Mahalingam M, Richards J, Selim M, Muzikansky A, Hoang M. An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma. Hum Pathol. 2012;43:1265-72 pubmed publisher
	Lenz J, Karasek P, Jarkovsky J, Muckova K, Dite P, Kala Z, et al. Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion. J Gastrointestin Liver Dis. 2011;20:389-96 pubmed
	Sana J, Zambo I, Skoda J, Neradil J, Chlapek P, Hermanova M, et al. CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines. Anal Cell Pathol (Amst). 2011;34:303-18 pubmed publisher
	Ren Z, Wang J, Zhu W, Guan Y, Zou C, Chen Z, et al. Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro. Exp Cell Res. 2011;317:2950-7 pubmed publisher
	Zhuang W, Long L, Ji W, Liang Z. Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy. Chin J Cancer. 2011;30:712-20 pubmed publisher
	Farahani R, Simonian M, Hunter N. Blueprint of an ancestral neurosensory organ revealed in glial networks in human dental pulp. J Comp Neurol. 2011;519:3306-26 pubmed publisher
	Zhuang W, Li B, Long L, Chen L, Huang Q, Liang Z. Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. Int J Cancer. 2011;129:2720-31 pubmed publisher
	Sellheyer K, Krahl D. Does the peritumoral stroma of basal cell carcinoma recapitulate the follicular connective tissue sheath?. J Cutan Pathol. 2011;38:551-9 pubmed publisher
	Kubinova S, Horak D, Kozubenko N, Vanecek V, Proks V, Price J, et al. The use of superporous Ac-CGGASIKVAVS-OH-modified PHEMA scaffolds to promote cell adhesion and the differentiation of human fetal neural precursors. Biomaterials. 2010;31:5966-75 pubmed publisher
	Sellheyer K, Krahl D. Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult human skin. J Am Acad Dermatol. 2010;63:93-113 pubmed publisher
	Rögelsperger O, Ekmekcioglu C, Jager W, Klimpfinger M, Konigsberg R, Krenbek D, et al. Coexpression of the melatonin receptor 1 and nestin in human breast cancer specimens. J Pineal Res. 2009;46:422-32 pubmed publisher
	Leonard B, Mastroeni D, Grover A, Liu Q, Yang K, Gao M, et al. Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol. 2009;515:269-94 pubmed publisher
	Veselska R, Hermanova M, Loja T, Chlapek P, Zambo I, Vesely K, et al. Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer. 2008;8:300 pubmed publisher
	Shah K, Hingtgen S, Kasmieh R, Figueiredo J, Garcia Garcia E, Martinez Serrano A, et al. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008;28:4406-13 pubmed publisher
	Wexler E. Markers of adult neural stem cells. Methods Mol Biol. 2008;438:243-68 pubmed publisher

product information

Catalog Number :

FCMAB313PE

Subcategory :

Stem Cell Research

Product Name :

Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P48681

Host Name :

Mouse

Antigen :

Nestin-PE

Clone :

10C2

Conjugate :

Phycoerythrin

Isotype :

IgG1κ

Product Description :

Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2

Cross Reactivity :

Human

Background :

Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma.

Immunogen :

Fusion protein

Specificity :

Antibody recognizes Human Nestin.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.