Milli-Mark™ Anti-Achaete Scute homolog 2 Antibody, clone 7E2 | EMD Millipore FCMAB285F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-Achaete Scute homolog 2 Antibody, clone 7E2

catalog :

FCMAB285F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

7E2

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB285F

Subcategory :

Stem Cell Research

Product Name :

Milli-Mark™ Anti-Achaete Scute homolog 2 Antibody, clone 7E2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q99929

Host Name :

Mouse

Antigen :

Achaete Scute homolog 2

Clone :

7E2

Conjugate :

FITC

Isotype :

IgG2bκ

Product Description :

Milli-Mark™ Anti-Achaete Scute homolog 2 Antibody, clone 7E2

Cross Reactivity :

Human

Background :

Achaete Scute homolog 2 (also known as mammalian aschaete-scute homolog 2 or Mash2) is a nuclear protein expressed specifically in the extravillous trophoblasts of developing placenta. Placental development involves control by the basic helix-loop-helix transcription factor Achaete Scute homolog 2, which may regulate HIF (hypoxia) in the formation of spongiotrophoblasts. Targeted mutagenesis of Achaete Scute homolog 2 yielded loss of function results in embryonic lethality at midgestation due to placental failure associated with a lack of spongiotrophoblasts and reduced labyrinthine trophoblast layers. In addition to healthy placental development, Achaete Scute proteins may also be involved in the determination of neuronal precursors in the central and peripheral nervous systems. Achaete Scute homolog 2 has also been implicated as a controller of intestinal stem cell fate and is essential for the maintenance of adult intestinal stem cells (Tanaka, M., et al., (1997) Dev Biol. 190(10):55-65).

ALT Names :

achaete-scute complex (Drosophila) homolog-like 2;achaete-scute complex homolog 2 (Drosophila);achaete-scute complex homolog-like 2;achaete-scute complex-like 2;achaete-scute complex-like 2 (Drosophila);mammalian achaete/scute homologue 2

Immunogen :

Histadine-tagged recombinant protein corresponding to human Achaete Scute homolog 2 near the C-terminus

Specificity :

This antibody recognizes Achaete Scute homolog 2 near the C-terminus.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.