Milli-Mark™ Anti-phospho-ATF2 (Thr69/71) Antibody, Alexa Fluor® 647, clone AW65 | EMD Millipore FCMAB271A6 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-phospho-ATF2 (Thr69/71) Antibody, Alexa Fluor® 647, clone AW65

catalog :

FCMAB271A6

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

AF647

antigen modification :

phosphorylated

clone name :

AW65

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB271A6

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Milli-Mark™ Anti-phospho-ATF2 (Thr69/71) Antibody, Alexa Fluor® 647, clone AW65

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15336

Host Name :

Mouse

Antigen :

phospho-ATF2 (Thr69/71)

Clone :

AW65

Conjugate :

AlexaFluor®647

Isotype :

IgG1

Product Description :

Milli-Mark™ Anti-phospho-ATF2 (Thr69/71) Antibody, Alexa Fluor® 647, clone AW65

Cross Reactivity :

Human

Background :

Activating transcription factor 2 (ATF2) is a member of the basic region leucine zipper (bZIP) family of proteins. Transcriptionally active ATF2 recognizes and binds to specific ATF/CRE motifs as homo- or heterodimers with other bZIP transcription factors of the ATF/CREB or AP-1 families. ATF2 is regulated by phosphorylation on Thr69/71. Two major kinases known to phosphorylate these sites are the two Stress Activated Protein Kinases (SAPK) Jun and p38 that are mitogen activated protein kinases (MAPKs). Phosphorylation and dimerization are required for the full transcriptional activity of ATF2. Transcriptional regulation by ATF2 has been implicated in mediating many diverse cellular processes such as growth, differentiation, immune and stress responses, inflammatory cytokine signaling, and oncogenic transformation.

ALT Names :

Cyclic AMP-dependent transcription factor ATF-2;cAMP-dependent transcription factor ATF-2;Activating transcription factor 2;cAMP response element-binding protein CRE-BP1;HB16;cAMP-responsive element-binding protein 2;CREB-2

Immunogen :

KLH-conjugated, synthetic peptide corresponding to phospho-threonine at residues 69 and 71 of human ATF2

Specificity :

Antibody recognizes phospho-ATF2-(Thr69/71) antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.