Milli-Mark™ Anti-GAPDH-FITC Antibody, clone 6C5 | EMD Millipore FCMAB252F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-GAPDH-FITC Antibody, clone 6C5

catalog :

FCMAB252F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

6C5

The same clone is also sold as:

LifeSpan Biosciences: LS-C85141, LS-C188577, LS-C52096, LS-C188574, LS-C185315, LS-B11003
Invitrogen: AM4300
OriGene: TA354651, 5G4-6C5
Abcam: ab8245
Santa Cruz Biotechnology: sc-32233
MyBioSource: MBS462002, MBS311206
Bio-Rad: MCA4739D680, MCA4739B, MCA4739, MCA4739D800, MCA4739P
Hytest: 5G4-6C5

reactivity :

human, rat

application :

western blot, immunohistochemistry, flow cytometry

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1	Oktyabri D, Ishimura A, Tange S, Terashima M, Suzuki T. DOT1L histone methyltransferase regulates the expression of BCAT1 and is involved in sphere formation and cell migration of breast cancer cell lines. Biochimie. 2016;123:20-31 pubmed publisher
immunohistochemistry; human; 1:10,000; fig 4	Lee Y, He H, Chen T, Lee S, Chang I, Hsing C, et al. The prognostic impact of RAP2A expression in patients with early and locoregionally advanced nasopharyngeal carcinoma in an endemic area. Am J Transl Res. 2015;7:912-21 pubmed
western blot; rat; 1:5000; fig 2a & b	Koppel I, Tuvikene J, Lekk I, Timmusk T. Efficient use of a translation start codon in BDNF exon I. J Neurochem. 2015;134:1015-25 pubmed publisher
western blot; human; fig 9	Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher

product information

Catalog Number :

FCMAB252F

Subcategory :

Metabolism

Product Name :

Milli-Mark™ Anti-GAPDH-FITC Antibody, clone 6C5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P04406

Host Name :

Mouse

Antigen :

GAPDH-FITC

Clone :

6C5

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-GAPDH-FITC Antibody, clone 6C5

Cross Reactivity :

Human

Background :

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in reasonably high levels in almost all tissues. As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a "high energy" intermediate used for the synthesis of ATP. Besides its cytoplasmic action in metabolism it is also involved in the initial stages of apoptosis or oxidative stress response where GAPDH is translocated to the nucleus. Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules. GAPDH has also been found to bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders including the beta-amyloid precursor protein and the huntingtin protein where decreased function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts. GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity. The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron. Binding domains also include one principally interacting with NAD+ and another interacting with glyceraldehyde 3-phosphate (GAP).

ALT Names :

GAPDH;G3PDH;GAPD;OK/SW-cl.12;MGC88685;G3PD;EC 1.2.1.12

Immunogen :

Glyceraldehyde-3-phosphate dehydrogenase purified from rabbit muscle

Specificity :

Antibody recognizes Human Glyceraldehyde-3-Phosphate Dehydrogenase.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.