Milli-Mark Anti-Bcl-2 Antibody, Alexa Fluor®488, clone AW604 | EMD Millipore FCMAB250A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark Anti-Bcl-2 Antibody, Alexa Fluor®488, clone AW604

catalog :

FCMAB250A4

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

AW604

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB250A4

Subcategory :

Apoptosis & Cancer

Product Name :

Milli-Mark Anti-Bcl-2 Antibody, Alexa Fluor®488, clone AW604

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10415

Host Name :

Mouse

Antigen :

Bcl-2

Clone :

AW604

Conjugate :

AlexaFluor®488

Isotype :

IgG2a

Product Description :

Milli-Mark Anti-Bcl-2 Antibody, Alexa Fluor®488, clone AW604

Cross Reactivity :

Human

Background :

Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 also regulates cell death by controlling the mitochondrial membrane permeability and appears to function in a feedback loop system with caspases. It appears to Inhibit caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Further understanding in how Bcl-2 functions and interacts with other proteins to promote or inhibit apoptosis may lead to new treatments for cancer, neurological disorders and autoimmune diseases.

Immunogen :

KLH-conjugated, synthetic peptide corresponding to human Bcl-2

Specificity :

Antibody recognizes Bcl-2.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.