This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Milli-Mark™ Anti-CD86-FITC Antibody, clone BU63
catalog :
FCMAB210F
quantity :
100 tests
clonality :
monoclonal
host :
mouse
conjugate :
FITC
reactivity :
human
application :
flow cytometry
product information
Catalog Number :
FCMAB210F
Subcategory :
Inflammation & Immunology
Product Name :
Milli-Mark™ Anti-CD86-FITC Antibody, clone BU63
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P42081
Host Name :
Mouse
Antigen :
CD86-FITC
Clone :
BU63
Conjugate :
FITC
Isotype :
IgG1κ
Product Description :
Milli-Mark™ Anti-CD86-FITC Antibody, clone BU63
Cross Reactivity :
Human
Background :
CD86 (B70/B7-2) is together with CD80 (B7/B7-1) natural ligands for CD28 and CD152 (CTLA-4). It is a 70 kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The CD86 cDNA encodes a 323 amino acid polypeptide composed of an N-terminal signal peptide, a 223 amino acid extracellular segment, a 23 amino acid transmembrane domain, and a 61 amino acid cytoplasmic domain (Azuma, 1993). The extracellular domain contains eight sites for N-linked glycosylation and the intracellular region has three potential sites for protein kinase C-dependent phosphorylation. The extracellular portion contains a V-set and a C2-set immunoglobulin-like domain (Azuma, 1993; Engel, 1994). CD86 is expressed on resting monocytes and dendritic cells and on activated T, NK, and B cells (Azuma, 1993; Engel, 1994; Caux, 1994; Engel, 1995). CD86 is rapidly induced on the surface of activated B cells. This suggests that it is the major CD28 ligand and may play an important role for costimulation of T cells in the primary immune response (Azuma, 1993; Thompson, 1995).
ALT Names :
T-lymphocyte activation antigen CD86;Activation B7-2 antigen;CTLA-4 counter-receptor B7.2;B70;FUN-1;BU63
Immunogen :
Human peripheral blood lymphocytes
Specificity :
Antibody recognizes Human CD86 antigen.
Package Size :
100 tests
Uses :
Flow Cytometry
Storage :
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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