Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57 | EMD Millipore FCMAB208P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

catalog :

FCMAB208P

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

HM57

The same clone is also sold as:

Santa Cruz Biotechnology: sc-53208
Abnova: MAB15368, MAB15369, MAB4515, MAB3843
LifeSpan Biosciences: LS-C44953, LS-C112540, LS-B4504
MilliporeSigma: SAB4700231
Novus Biologicals: NB100-64347
Exbio: 11-530-C100, 1P-530-T025, 1F-530-T100, 1A-530-T025, 1F-530-T025, 1P-530-T100, 1A-530-T100, 11-530-C025
OriGene: DM118-05, AM01322RP-N, DM118, AM01322PU-S, AM01322SU-N, AM01322PU-N, AM01322RP-T, AM01322PU-T, TA353063L, AM01322FC-N
Abcam: ab62650
Invitrogen: MA1-81870, MA5-16711, MA5-16710, MA5-28540
Bio-Rad: MCA2538, MCA2538A488, MCA2538F, MCA2538GA, MCA2538PE, MCA2538PET, MCA2538A647, MCA2538T, MCA2538A700, MCA2538H, MCA2538A647T

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB208P

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11912

Host Name :

Mouse

Antigen :

CD79αcy-PE

Clone :

HM57

Conjugate :

Phycoerythrin

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

Cross Reactivity :

Human

Background :

CD79 is a disulphide-linked transmembrane heterodimer with a molecular mass of 82-95 kDa belonging to the immunoglobulin superfamily. It comprises the two glycoproteins, CD79α, with a molecular mass of 40-45 kDa, and CD79β, with a molecular mass of 37 kDa. CD79 is non-covalently associated with surface Ig, forming the B-cell receptor complex, which is required for antigen recognition. The expression of CD79 is largely restricted to B-lineage cells (Pilozzi,1998). In precursor B cells, the CD79 protein chains are already expressed in the cytoplasm (CyCD79). Surface expression of CD79 begins at the pro-B cell stage and persists throughout the B-cell differentiation. CD79α is more strongly expressed by B cells in the follicular mantle zone than by germinal centre B cells, suggesting that activation of mature B cells downregulates CD79 expression. CD79 expression ceases around the onset of plasma cell differentiation, with only a proportion of plasma cells containing CD79 (Comans-Bitter, 1997)(Nakamura, 1997). The HM57 antibody was clustered as Anti-CD79αcy at the Fifth International Workship on Human Leucocyte Differentiation Antigens (Engel, 1995).

ALT Names :

B-cell antigen receptor complex-associated protein alpha chain;Ig-alpha;MB-1 membrane glycoprotein;Surface IgM-associated protein;Membrane-bound immunoglobulin-associated protein

Immunogen :

Synthetic peptide sequence comprising amino acids 202-216 of the CD79α protein. This oligopeptide represents an intra-cytoplasmic C-terminal part of the protein.

Specificity :

Antibody recognizes Human CD79αcy antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.