Milli-Mark™ Anti-CD54-FITC Antibody, clone 6.5B5 | EMD Millipore FCMAB198F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD54-FITC Antibody, clone 6.5B5

catalog :

FCMAB198F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

6.5B5

The same clone is also sold as:

Santa Cruz Biotechnology: sc-18853

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB198F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD54-FITC Antibody, clone 6.5B5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05362

Host Name :

Mouse

Antigen :

CD54-FITC

Clone :

6.5B5

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD54-FITC Antibody, clone 6.5B5

Cross Reactivity :

Human

Background :

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).

ALT Names :

Intercellular adhesion molecule 1;ICAM-1;Major group rhinovirus receptor

Immunogen :

TNF-activated human umbilical vein endothelial cells

Specificity :

Antibody recognizes Human CD54 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.