Milli-Mark™ Anti-CD42b-PE Antibody, clone AN51 | EMD Millipore FCMAB196P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD42b-PE Antibody, clone AN51

catalog :

FCMAB196P

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

AN51

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB196P

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD42b-PE Antibody, clone AN51

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P07359

Host Name :

Mouse

Antigen :

CD42b-PE

Clone :

AN51

Conjugate :

Phycoerythrin

Isotype :

IgG2aκ

Product Description :

Milli-Mark™ Anti-CD42b-PE Antibody, clone AN51

Cross Reactivity :

Human

Background :

CD42b is a 145 kDa protein, which together with CD42c forma a 160 kDa heterodimer composed of an alpha-chain and a beta-chain, respectively. The subunits are linked together by a disulphide bond. CD42b and CD42c forms a non-covalent complex together with CD42a and CD42d in the platelet plasma membrane. The CD42 complex serves as a receptor for von Willebrand factor and thrombin and mediates adhesion of platelets to subendothelial matrices (exposed upon damage to the endothelium) at high shear rates. The binding sites for von Willebrand factor and thrombin lies on CD42b (de Haas, 2002). CD42 is expressed on megakarytocytes and platelets (McMichael, 1981).

ALT Names :

Platelet glycoprotein Ib alpha chain;Glycoprotein Ibalpha;GP-Ib alpha;GPIb-alpha;GPIbA;Antigen CD42b-alpha

Immunogen :

Mixture of human platelets and lymphocytes.

Specificity :

Antibody recognizes Human CD42b antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.