Milli-Mark™ Anti-CD41-FITC Antibody, clone 5B12 | EMD Millipore FCMAB195F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD41-FITC Antibody, clone 5B12

catalog :

FCMAB195F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

5B12

The same clone is also sold as:

International Blood Group Reference Laboratory: 9461FI, 9461PA

reactivity :

human

application :

flow cytometry

citations: 1

Reference
David A, Yewdell J. Applying the ribopuromycylation method to detect nuclear translation. Methods Mol Biol. 2015;1228:133-42 pubmed publisher

product information

Catalog Number :

FCMAB195F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD41-FITC Antibody, clone 5B12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08514

Host Name :

Mouse

Antigen :

CD41-FITC

Clone :

5B12

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD41-FITC Antibody, clone 5B12

Cross Reactivity :

Human

Background :

CD41 is the α-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-binding sites and is entirely extracellular, while the β-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).

ALT Names :

Integrin alpha-IIb;Platelet membrane glycoprotein IIb;GPalpha IIb;GPIIb

Immunogen :

Normal human platelets

Specificity :

Antibody recognizes Human CD41 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.