Milli-Mark™ Anti-CD38-FITC Antibody, clone AT13/5 | EMD Millipore FCMAB194F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD38-FITC Antibody, clone AT13/5

catalog :

FCMAB194F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

AT13/5

The same clone is also sold as:

Absolute Antibody: Ab00289-23.0, Ab00289-1.1
Invitrogen: MA5-16578, MA5-16577
OriGene: SM1106PT, SM1106P, SM1106B, SM1106R, SM1106A
Bio-Rad: MCA1019T, MCA1019A647T, MCA1019SBV515, MCA1019A488, MCA1019A647, MCA1019A488T, MCA1019, MCA1019P750, MCA1019B, MCA1019PE, MCA1019XZ
LifeSpan Biosciences: LS-C43216, LS-C43213, LS-C43218, LS-C43214
Santa Cruz Biotechnology: sc-59028

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB194F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD38-FITC Antibody, clone AT13/5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P28907

Host Name :

Mouse

Antigen :

CD38-FITC

Clone :

AT13/5

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD38-FITC Antibody, clone AT13/5

Cross Reactivity :

Human

Background :

CD38 is a 45 kDa type II integral membrane glycoprotein consisting of an N-terminal 20 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 257 amino acid extracellular domain. CD38 is associated with different molecules in different cell types and these unique combinations cause unique cell-type specific signaling. One of the known ligands that activates CD38-mediated signaling is CD31 (Deaglio, 2001). CD38 is expressed by a number of different cell types and the pattern of expression often changes with differentiation and maturation. Thus, CD38 expression is found during early stages of B and T-cell differentiation, is lacking during the later intermediate stages, and is regained near the end of maturation. CD38 is expressed at variable levels on the majority of hematopoietic cells, prevalently during early differentiation and activation, and it is expressed strongly on plasma cells (Jackson, 1990; Terstappen, 1990; Morra, 1997). CD38-postive cell types outside the hematopoietic system include subsets from the gut, brain, prostate, pancreas, bone, eye, and muscle (Deaglio, 2001). CD38 is expressed on approximately 60% of CD34-positive peripheral blood mononuclear cells. The least mature CD34-postive cells are characterized by a lack of CD38 (Herbein, 1994). Anti-CD38, AT13/5 was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD38 (Morra, 1997).

ALT Names :

ADP-ribosyl cyclase 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10

Immunogen :

Namalwa cells (B lymphocyte cell line from Burkitt's lymphoma)

Specificity :

Antibody recognizes Human CD38 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.