Milli-Mark™ Anti-CD27-FITC Antibody, clone M-T271 | EMD Millipore FCMAB191F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD27-FITC Antibody, clone M-T271

catalog :

FCMAB191F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

M-T271

The same clone is also sold as:

Miltenyi Biotec: 130-113-634, 130-113-630, 130-114-152, 130-113-629, 130-113-631, 130-113-627, 130-113-635, 130-114-158, 130-114-161, 130-114-160, 130-113-632, 130-114-159, 130-114-156, 130-114-157, 130-114-155, 130-113-633, 130-113-626, 130-113-628, 130-114-153
LifeSpan Biosciences: LS-C134358, LS-C134359, LS-C134361, LS-C134360, LS-B7793
Santa Cruz Biotechnology: sc-19653
BD Biosciences: 560609, 561786, 562297, 561222, 560458, 562513, 562324, 560222, 561400, 557330, 555441, 560986, 560612, 558664, 557329, 561408, 555439, 560611, 555440, 560223, 655157, 560448, 560985, 561223
BioLegend: 356426, 356432, 356416, 356409, 356405, 356433, 356403, 356421, 356406, 356436, 356401, 356431, 356423, 356415, 356430, 356407, 356404, 356427, 356418, 356420, 356413, 356424, 356429, 356434, 356412, 356410, 356408, 356428, 356417, 356411, 356414, 356422, 356435
Abnova: MAB6903, MAB16281

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB191F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD27-FITC Antibody, clone M-T271

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P26842

Host Name :

Mouse

Antigen :

CD27-FITC

Clone :

M-T271

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD27-FITC Antibody, clone M-T271

Cross Reactivity :

Human

Background :

CD27, a member of the nerve growth factor receptor (NGFR) superfamily, is a type I transmembrane protein consisting of a disulphide-linked 120 kDa homodimer (Bigler, 1988; Sugita, 1992; Morimoto, 1995). CD27 is expressed on mature thymocytes and on the majority of human peripheral blood T cells, on both CD4+ and CD8+ subsets. CD27 is also expressed on activated B cells and a fraction of resting natural killer (NK) cells (Maurer, 1990; Sugita, 1992). Among CD4+ T cells, CD27 is preferentially expressed on unprimed CD4+CD45RA+CD45R0- T cells, while primed CD4+CD45RA-CD45R0+ T cells express low levels of CD27 (Sugita, 1992). During activation, the expression of CD27 is increased on B cells and unprimed T cells, while primed T cells have a relatively low capacity for upregulation of CD27 (Morimoto, 1995; Hintzen, 1994). The activation is also accompanied by the appearance of a 32 kDa soluble form of CD27 (sCD27) found in supernatants of activated lymphocytes (Hintzen, 1994). CD27 is believed to play a role in T cell activation, since the expression is upregulated during T cell activation (Bigler, 1988; Sugita, 1992; Morimoto, 1995; Maurer, 1990; Hintzen, 1994; Lens, 1995).

ALT Names :

CD27 antigen;CD27L receptor;T-cell activation antigen CD27;T14;Tumor necrosis factor receptor superfamily member 7

Immunogen :

Leukemic peripheral blood T cells from a patient with chronic T cell leukemia (T-CLL)

Specificity :

Antibody recognizes Human CD27 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.