Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1 | EMD Millipore FCMAB186F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

catalog :

FCMAB186F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

B-Ly1

The same clone is also sold as:

Invitrogen: A15430
OriGene: AM08155PU-N, AM08154PU-N, AM08154BT-N, AM08154FC-N, AM08154RC7-N, AM08154RP-N, AM08154AC7-N, AM08155FC-N, AM08155RP-N
Santa Cruz Biotechnology: sc-19990
Abnova: MAB5996, MAB5992, MAB5991, MAB5993, MAB5614, MAB5998, MAB5997, MAB5994, MAB5615, MAB5995, MAB5990
Abcam: ab25607
LifeSpan Biosciences: LS-C351485, LS-C122962, LS-C351486, LS-C351481, LS-C351490, LS-C351488, LS-C351495, LS-C351489, LS-C196194, LS-C195566, LS-C196199, LS-C204076, LS-C351483, LS-C196195, LS-C351493, LS-C351487, LS-C196198

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB186F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11836

Host Name :

Mouse

Antigen :

CD20 -FITC

Clone :

B-Ly1

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

Cross Reactivity :

Human

Background :

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B cells, but is lost following differentiation into plasma cells (Tedder, 1994). In resting B cells, CD20 appears in a 33 kDa non-phosphorylated form. After mitogen stimulation, CD20 becomes heavily phosphorylated (35-37 kDa isoforms), and it is a dominant phosphoprotein in activated B cells and B-cell lines (Zhou, 1995). The long N- and C-terminal ends of the protein are located on the cytoplasmic side of the membrane and only a minor portion of the protein is exposed on the cell surface (Tedder, 1994). Antibodies reacting with CD20 cytoplasmic epitopes are designated CD20cy (Zhou, 1995). It is suggested that CD20 plays a direct role in regulating the transmembrane conductive Ca 2+ flux of B cells which indicates a possible function for CD20 as a regulator of proliferation and differentiation (Tedder, 1994).

ALT Names :

Membrane-spanning 4-domains subfamily A member 1 B-lymphocyte surface antigen B1 Leukocyte surface antigen Leu-16 Bp35 CD_antigen=CD20

Specificity :

Antibody recognizes Human CD20 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.