Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47 | EMD Millipore FCMAB180F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47

catalog :

FCMAB180F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

WM-47

reactivity :

human

application :

flow cytometry

citations: 1

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:20; fig 1	Fiddler C, Parfrey H, Cowburn A, Luo D, Nash G, Murphy G, et al. The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion. PLoS ONE. 2016;11:e0160108 pubmed publisher

product information

Catalog Number :

FCMAB180F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15144

Host Name :

Mouse

Antigen :

CD13-FITC

Clone :

WM-47

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47

Cross Reactivity :

Human

Background :

CD13 is a 150 kDa Type II integral membrane protein composed of 967 amino acids (Turni, 2002; Ashmun, 1995; Look, 1989). CD13 is identical in structure to aminopeptidase N, a membrane-bound zinc-binding metalloprotease (Turni, 2002). CD13 is expressed on the surface of committed granulocyte-monocyte progenitors (CFU-GM) and by cells of the granulocyte and monocyte lineages at all stages of differentiation (Turni, 2002; Ashmun, 1995; Look, 1989). The antigen is also expressed on a small proportion of large granular lymphocytes, but not on B or T cells (Ashmun, 1995; Look, 1989). Further, CD13 is expressed on some non-hematopoietic cells including fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining the bile duct canaliculi (Turni, 2002; Ashmun, 1995; Look, 1989). Anti-CD13, WM-47, was included in the Fourth and Fifth International Workshop and Conference on Leucocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD 13 (Ashmun, 1995; Look, 1989).

ALT Names :

Aminopeptidase N (AP-N), hAPN, Alanyl aminopeptidase, Microsomal aminopeptidase, Aminopeptidase M (AP-M), gp150, Myeloid plasma membrane glycoprotein CD13

Immunogen :

Leukaemic cells from a case of chronic myeloid leukaemia (CML).

Specificity :

Antibody recognizes Human CD13 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.