Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c | EMD Millipore FCMAB178P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

catalog :

FCMAB178P

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

2LPM19c

The same clone is also sold as:

Invitrogen: MA1-91659
Santa Cruz Biotechnology: sc-20050

reactivity :

human

application :

flow cytometry

citations: 3

Reference
Jerke U, Rolle S, Purfürst B, Luft F, Nauseef W, Kettritz R. ?2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells. J Biol Chem. 2013;288:12910-9 pubmed publisher
Son H, Kim J, Hahn Y, Seo S. Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia. Mol Cell Biol. 2012;32:3681-94 pubmed publisher
Lee H, Koo B, Kim Y, Jeon O, Kim D. Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes. FASEB J. 2012;26:3084-95 pubmed publisher

product information

Catalog Number :

FCMAB178P

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11215

Host Name :

Mouse

Antigen :

CD11B-PE

Clone :

2LPM19c

Conjugate :

Phycoerythrin

Isotype :

IgG1κ

Product Description :

Milli-Mark™ Anti-CD11B-PE Antibody, clone 2LPM19c

Cross Reactivity :

Human

Background :

CD11b is the 165 kDa α-chain of the Mac-1 complex. The molecule, also called CR3, functions as a cell surface receptor for the C3bi complement fragment. There is evidence that CD11b can bind fibrinogen in addition to C3bi (Wright,1988). Two binding sites have now been reported, one recognizing lipopolysaccharide, and the other protein ligands containing the arg-gly-asp sequence (Wright, 1989). Binding of the coagulation factor X has also been suggested as an additional receptor role of CD11b (Altieri,1988). This protein belings to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens, which shares a common β-chain with a MW of 95 kDa (CD18). Besides the C3bi receptor, this protein family contains two other members, leucocyte function associated-1 (LFA-1, C11a) antigen and p150,95 protein (CD11c) (Sanchez-Madrid,1983).

ALT Names :

Integrin alpha-M;Cell surface glycoprotein MAC-1 subunit alpha;CR-3 alpha chain;Leukocyte adhesion receptor MO1;Neutrophil adherence receptor;CD11 antigen-like family member B

Immunogen :

Purified iC3b receptor.

Specificity :

Antibody recognizes Human CD11b antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.