Milli-Mark Anti-CD8 -FITC Antibody, clone DK25 | EMD Millipore FCMAB176F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark Anti-CD8 -FITC Antibody, clone DK25

catalog :

FCMAB176F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

DK25

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB176F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark Anti-CD8 -FITC Antibody, clone DK25

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01732

Host Name :

Mouse

Antigen :

CD8 -FITC

Clone :

DK25

Conjugate :

FITC

Isotype :

IgG1κ

Product Description :

Milli-Mark Anti-CD8 -FITC Antibody, clone DK25

Cross Reactivity :

Human

Background :

CD8 is a 68 kDa disulphide-linked, transmembrane glycoprotein. The CD8 molecule serves as a receptor for MHC class I molecules and can mediate a function as a coreceptor in TCR-ligand binding and T-cell activation. Its cytoplasmic part is associated with the p56Ick tyrosine kinase (Nakuchi, 1997). CD8 is expressed by the great majority of cortical thymocytes and approximately 30% of medullary thymocytes, and by class I major histocompatibility complex restricted, mature suppressor/cytotoxic T cells. In addition a proportion of gamma delta T cells and NK cells express CD8 (Nakuchi, 1997). Thus, CD8 is expressed by about 25-35% of peripheral T cells, and about 30% of NK cells express low levels of CD8 (Leong, 1999). The specificity of Anti-CD8, DK25, is equivalent to that of the CD8-clustered antibodies OKT8 and Leu-2a (Stein, 1984).

Specificity :

Antibody recognizes Human CD8 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.