Milli-Mark Anti-CD4 -FITC Antibody, clone MT310 | EMD Millipore FCMAB170F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark Anti-CD4 -FITC Antibody, clone MT310

catalog :

FCMAB170F

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

MT310

The same clone is also sold as:

Novus Biologicals: NBP2-52706-0.2mg, NBP2-52663-0.2mg
Santa Cruz Biotechnology: sc-19641
Absolute Antibody: Ab00217-1.1, Ab00217-35.0, Ab00217-37.0, Ab00217-36.0, Ab00217-23.0, Ab00217-26.0, Ab00217-10.0

reactivity :

human

application :

flow cytometry

product information

Catalog Number :

FCMAB170F

Subcategory :

Inflammation & Immunology

Product Name :

Milli-Mark Anti-CD4 -FITC Antibody, clone MT310

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P01730

Host Name :

Mouse

Antigen :

CD4 -FITC

Clone :

MT310

Conjugate :

FITC

Isotype :

IgG1

Product Description :

Milli-Mark Anti-CD4 -FITC Antibody, clone MT310

Cross Reactivity :

Human

Background :

CD4 is a 55 kDa glycoprotein with four immunoglobulin-like external domains, a transmembrane domain and a highly conserved intracellular domain (Leong, 1999). CD4 acts as a coreceptor in MHC class II-restricted antigen-induced T-cell activation. Further, CD4 has a role in the regulation of T-B lymphocyte adhesion in the absence of antigen recognition, and in thymic differentiation (Piatier-Tonneau, 2002). CD4 is expressed on thymocyte subsets, it marks helper/inducer T cells, and it is expressed in 55-65% of mature peripheral T cells. Subpopulations of suppressor or cytotoxic T cells can be identified among CD4-positive T cells. CD4 is also expressed on monocytes/macrophages, Langerhans cells and other dendritic cells. CD4 is not expressed on B cells. Anti-CD4, MT310, was included in the Second International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD4 antigen (Miedema, 1986).

ALT Names :

T-cell surface antigen T4/Leu-3

Specificity :

Antibody recognizes Human CD4 antigen.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.