Milli-Mark Anti-Beta-catenin-PE Antibody, clone 7F7.2 | EMD Millipore FCMAB120P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark Anti-Beta-catenin-PE Antibody, clone 7F7.2

catalog :

FCMAB120P

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

7F7.2

reactivity :

mouse

application :

flow cytometry

product information

Catalog Number :

FCMAB120P

Subcategory :

Cell Signaling

Product Name :

Milli-Mark Anti-Beta-catenin-PE Antibody, clone 7F7.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35222

Host Name :

Mouse

Antigen :

Beta-catenin-PE

Clone :

7F7.2

Conjugate :

Phycoerythrin

Isotype :

IgG1κ

Product Description :

Milli-Mark Anti-Beta-catenin-PE Antibody, clone 7F7.2

Cross Reactivity :

Mouse

Background :

Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as α-catenin and β-catenin. α-Catenin can bind to β-catenin and can also bind actin. β-catenin binds the cytoplasmic domain of some cadherins. When β-catenin was sequenced it was found to be a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain which is specialized for protein-protein binding. An increase in β-catenin production has been noted in those people who have Basal Cell Carcinoma and leads to the increase in proliferation of related tumors. When β-catenin is not associated with cadherins and α-catenin, it can interact with other proteins such as Catenin Beta Interacting Protein 1 (ICAT) and adenomatosis polyposis coli (APC). Recent evidence suggests that β-catenin plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), liver regeneration following partial hepatectomy, HGF-induced hepatomegaly, liver zonation, and pathogenesis of liver cancer.

ALT Names :

Beta Catenin Catenin (cadherin-associated protein), beta 1

Immunogen :

Full length, GST-tagged recombinant beta catenin.

Specificity :

Antibody recognizes Beta-catenin.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.