Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate | EMD Millipore FCMAB113A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

catalog :

FCMAB113A4

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

10H11.2

reactivity :

human, mouse

application :

immunocytochemistry, flow cytometry

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Kandasamy K, Narayanan K, Ni M, Du C, Wan A, Zink D. Polysulfone membranes coated with polymerized 3,4-dihydroxy-l-phenylalanine are a versatile and cost-effective synthetic substrate for defined long-term cultures of human pluripotent stem cells. Biomacromolecules. 2014;15:2067-78 pubmed publisher
	Shukla V, Rao M, ZHANG H, Beers J, Wangsa D, Wangsa D, et al. ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Res. 2017;77:6267-6281 pubmed publisher
	Xia H, Bodempudi V, Benyumov A, Hergert P, Tank D, Herrera J, et al. Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis. Am J Pathol. 2014;184:1369-83 pubmed publisher
	Beers J, Gulbranson D, George N, Siniscalchi L, Jones J, Thomson J, et al. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Protoc. 2012;7:2029-40 pubmed publisher
	Zuk P. The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used. J Cell Biochem. 2009;106:867-77 pubmed publisher

product information

Catalog Number :

FCMAB113A4

Subcategory :

Stem Cell Research

Product Name :

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q01860

Host Name :

Mouse

Antigen :

Oct 4

Clone :

10H11.2

Conjugate :

AlexaFluor®488

Isotype :

IgG1

Product Description :

Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate

Cross Reactivity :

Human

Background :

Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent embryonic stem (ES) and embryonic carcinoma (EC) cells express Oct-4. Additionally, murine embryonic germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 expression by human EG cells is not known.

ALT Names :

Octamer-binding transcription factor 3;POU class 5 homeobox 1;POU domain class 5, transcription factor 1;POU domain, class 5, transcription factor 1;POU-type homeodomain-containing DNA-binding protein;octamer-binding transcription factor-3

Immunogen :

Recombinant GST fusion protein, human Oct-4 (aa 1-134).

Specificity :

Reacts with human Oct-4.

Package Size :

100 tests

Uses :

Flow Cytometry;Immunocytochemistry

Storage :

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt