Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2 Alexa Fluor® 488 | EMD Millipore FCMAB106A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2 Alexa Fluor® 488

catalog :

FCMAB106A4

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

5C9.2

reactivity :

human, mouse

application :

western blot, flow cytometry

product information

Catalog Number :

FCMAB106A4

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2 Alexa Fluor® 488

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42224

Host Name :

Mouse

Antigen :

Phospho-Stat1 (Tyr701)

Clone :

5C9.2

Conjugate :

AlexaFluor®488

Isotype :

IgG1κ

Product Description :

Anti-Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2 Alexa Fluor® 488

Cross Reactivity :

Human;Mouse;Rat

Background :

STATs (Signal-Transducing Activators of Transcription) are the principle substrates of JAK kinases, and mediators of cytokine signaling. STAT proteins have SH2 domains, and once phosphorylated by JAK kinases, STATs dimerize in a head-to-tail fashion, through their SH2 domains. STAT1 is a critical mediator of IFN signaling, STAT4 is specific to IL-12, STAT6 is activated primarily by IL-4 and IL-13, while STAT5 A and B appear to be most important to the function of growth hormone and prolactin. STAT3 is involved in multiple signaling pathways, and mice deficient in it are not viable. In addition to tyrosine phosphorylation, many STAT proteins are targets of Ser/Thr kinases, and those phosphorylation events potentiate STAT-induced transcription. The phosphorylation state of STATs can be monitored by phosphorylation state-specific antibodies.

ALT Names :

Transcription factor ISGF-3 components p91/p84 signal transducer and activator of transcription 1

Immunogen :

KLH-conjugated linear peptide corresponding to the region around phosphorylated tyrosine 701.

Specificity :

Antibody recognizes STAT1 phosphorylated at Tyr701.

Package Size :

100 tests

Uses :

Flow Cytometry;Western Blotting

Storage :

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. Protect from light.