phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488 | EMD Millipore FCMAB104A4 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488

catalog :

FCMAB104A4

quantity :

100 tests

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

3H10

reactivity :

human

application :

flow cytometry

citations: 19

Reference
Traboulsi H, Davoli S, Catez P, Egly J, Compe E. Dynamic partnership between TFIIH, PGC-1Î± and SIRT1 is impaired in trichothiodystrophy. PLoS Genet. 2014;10:e1004732 pubmed publisher
Kogata N, Oliemuller E, Wansbury O, Howard B. Neuregulin-3 regulates epithelial progenitor cell positioning and specifies mammary phenotype. Stem Cells Dev. 2014;23:2758-70 pubmed publisher
Wohlan K, Goy S, Olling A, Srivaratharajan S, Tatge H, Genth H, et al. Pyknotic cell death induced by Clostridium difficile TcdB: chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity. Cell Microbiol. 2014;16:1678-92 pubmed publisher
VanLeeuwen J, Rafalovich I, Sellers K, Jones K, Griffith T, Huda R, et al. Coordinated nuclear and synaptic shuttling of afadin promotes spine plasticity and histone modifications. J Biol Chem. 2014;289:10831-42 pubmed publisher
Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
Ahn H, Choi J, Kim K, Kim H, Choi S, Park S, et al. Phase II study of pazopanib monotherapy in metastatic gastroenteropancreatic neuroendocrine tumours. Br J Cancer. 2013;109:1414-9 pubmed publisher
Iovino N, Ciabrelli F, Cavalli G. PRC2 controls Drosophila oocyte cell fate by repressing cell cycle genes. Dev Cell. 2013;26:431-9 pubmed publisher
Stewart C, Wang Y, Bonilla Claudio M, Martin J, Gonzalez G, Taketo M, et al. CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. Mol Endocrinol. 2013;27:1442-54 pubmed publisher
Ren K, Lu J, Porollo A, Du C. Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice. J Biol Chem. 2012;287:14792-802 pubmed publisher
Dronamraju R, Mason J. MU2 and HP1a regulate the recognition of double strand breaks in Drosophila melanogaster. PLoS ONE. 2011;6:e25439 pubmed publisher
Yoshida M, Feng L, Grimbert F, Rangarajan K, Buggele W, Copenhagen D, et al. Overexpression of neurotrophin-3 stimulates a second wave of dopaminergic amacrine cell genesis after birth in the mouse retina. J Neurosci. 2011;31:12663-73 pubmed publisher
Stewart C, Fisher S, Wang Y, Stewart M, Hewitt S, Rodriguez K, et al. Uterine gland formation in mice is a continuous process, requiring the ovary after puberty, but not after parturition. Biol Reprod. 2011;85:954-64 pubmed publisher
Koning M, Werker P, van Luyn M, Harmsen M. Hypoxia promotes proliferation of human myogenic satellite cells: a potential benefactor in tissue engineering of skeletal muscle. Tissue Eng Part A. 2011;17:1747-58 pubmed publisher
Matthess Y, Raab M, Sanhaji M, Lavrik I, Strebhardt K. Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity. Mol Cell Biol. 2010;30:5726-40 pubmed publisher
Suzuki K, Nakashima M, Yamashita S. Dynamics of ionizing radiation-induced DNA damage response in reconstituted three-dimensional human skin tissue. Radiat Res. 2010;174:415-23 pubmed publisher
Ciccia A, Bredemeyer A, Sowa M, Terret M, Jallepalli P, Harper J, et al. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart. Genes Dev. 2009;23:2415-25 pubmed publisher
Oda H, Okamoto I, Murphy N, Chu J, Price S, Shen M, et al. Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol. 2009;29:2278-95 pubmed publisher
Pomerening J, Ubersax J, Ferrell J. Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF. Mol Biol Cell. 2008;19:3426-41 pubmed publisher
Mitra S, Mikolon D, Molina J, Hsia D, Hanson D, Chi A, et al. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 2006;25:5969-84 pubmed

product information

Catalog Number :

FCMAB104A4

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16695

Host Name :

Mouse

Antigen :

phospho H3 (Ser10)

Clone :

3H10

Conjugate :

AlexaFluor®488

Isotype :

IgG1κ

Product Description :

Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3S10P;Histone H3 (phospho S10);H3 histone family, member T histone 3, H3 histone cluster 3, H3

Immunogen :

A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3.

Specificity :

Histone H3 phosphorylated at Ser10

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.