Milli-Mark™ Anti-NR2B-FITC Antibody | EMD Millipore FCABS332F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Milli-Mark™ Anti-NR2B-FITC Antibody

catalog :

FCABS332F

quantity :

100 tests

clonality :

polyclonal

host :

rabbit

conjugate :

FITC

reactivity :

human, dog, cow

application :

flow cytometry

product information

Catalog Number :

FCABS332F

Subcategory :

Neuroscience

Product Name :

Milli-Mark™ Anti-NR2B-FITC Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q13224

Host Name :

Rabbit

Antigen :

NR2B-FITC

Conjugate :

FITC

Isotype :

IgG

Product Description :

Milli-Mark™ Anti-NR2B-FITC Antibody

Cross Reactivity :

Rabbit;Bovine;Canine;Human;Monkey;Rat

Background :

NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B or NR2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA). Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease, epilepsy and ischemic neuronal cell death.

ALT Names :

N-methyl D-aspartate receptor subtype 2B;N-methyl-D-aspartate receptor subunit 2B;N-methyl-D-aspartate receptor subunit 3;glutamate receptor subunit epsilon-2;glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Immunogen :

Linear peptide corresponding to mouse NR2B.

Specificity :

Antibody recognizes Mouse NR2B.

Package Size :

100 tests

Uses :

Flow Cytometry

Storage :

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.