Adenovirus 2 E1A Mouse mAb (M73) | EMD Millipore DP11-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Adenovirus 2 E1A Mouse mAb (M73)

catalog :

DP11-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

unidentified adenovirus

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; unidentified adenovirus; fig 2	Romanov V, Brichkina A, Morrison H, Pospelova T, Pospelov V, Herrlich P. Novel mechanism of JNK pathway activation by adenoviral E1A. Oncotarget. 2014;5:2176-86 pubmed

product information

Catalog Number :

DP11-100UG

Category :

Antibodies

Subcategory :

Infectious Diseases

Product Name :

Anti-Adenovirus 2 E1A Mouse mAb (M73)

Product Type :

Antibodies

Clonality :

Monoclonal

Host Name :

Clone :

M73

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Adenovirus 2 E1A Mouse mAb (M73)

Cross Reactivity :

Adenovirus Infected Cells

Background :

The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the leftmost 11% of the viral genome and consists of two transcriptional units, E1A and E1B. Region E1A is sufficient for partial transformation and immortalization of primary cells, whereas the E1B function is normally required for complete transformation. In addition to their essential role in transformation, E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection, and are able to either activate or repress the transcription of specific cellular genes. E1A oncogene proteins form specific complexes with cellular proteins including the anti-oncogene retinoblastoma susceptibility gene product, p105. The consequence of this interaction is inhibition of the cell cycle arresting function of p105.

ALT Names :

Adenovirus 2 E1A Mouse mAb (M73)

Immunogen :

adenovirus 2 E1A protein

Specificity :

Recognizes adenovirus-infected cells and tissue.

Package Size :

100 ug

Uses :

IH, WB, IC, IF, IP, IH(P)

Storage :

Following initial use, aliquot and freeze (-20°C) for long-term storage. Do not freeze.