SV40 T Antigen (Ab-2) Mouse mAb (PAb416) | EMD Millipore DP02-200UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SV40 T Antigen (Ab-2) Mouse mAb (PAb416)

catalog :

DP02-200UG

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Song Y, Sullivan T, Klarmann K, Gilbert D, O Sullivan T, Lu L, et al. RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice. PLoS ONE. 2017;12:e0171510 pubmed publisher

product information

Catalog Number :

DP02-200UG

Category :

Antibodies

Subcategory :

Infectious Diseases

Product Name :

Anti-SV40 T Antigen (Ab-2) Mouse mAb (PAb416)

Product Type :

Antibodies

Clonality :

Monoclonal

Host Name :

Clone :

PAb416

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-SV40 T Antigen (Ab-2) Mouse mAb (PAb416)

Cross Reactivity :

Sv40 Infected Cells

Background :

SV40 T Ag (Ab-2) is a mouse monoclonal antibody with specificity for antigenic determinants unique to the SV40 large T antigen and non-reactive with SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular transforming protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the p105 product of the retinoblastoma susceptibility gene.

ALT Names :

SV40 T Antigen (Ab-2) Mouse mAb (PAb416)

Immunogen :

purified SV40 large T-antigen

Specificity :

Recognizes the ~94 kDa SV40 large T antigen.

Package Size :

200 ug

Uses :

WB, IF, IP, IH(P)

Storage :

Do not freeze