SV40 T Antigen (Ab-1) Mouse mAb (PAb419) | EMD Millipore DP01-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SV40 T Antigen (Ab-1) Mouse mAb (PAb419)

catalog :

DP01-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; fig 5	Fliedl L, Manhart G, Kast F, Katinger H, Kunert R, Grillari J, et al. Novel human renal proximal tubular cell line for the production of complex proteins. J Biotechnol. 2014;176:29-39 pubmed publisher

product information

Catalog Number :

DP01-100UG

Category :

Antibodies

Subcategory :

Infectious Diseases

Product Name :

Anti-SV40 T Antigen (Ab-1) Mouse mAb (PAb419)

Product Type :

Antibodies

Clonality :

Monoclonal

Host Name :

Clone :

PAb419

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-SV40 T Antigen (Ab-1) Mouse mAb (PAb419)

Cross Reactivity :

Sv40 Infected Cells

Background :

SV40 T Ag (Ab-1) is a mouse monoclonal antibody with specificity for antigenic determinants localized to the amino terminal domain of the SV40 large T antigen. The sequences recognized by this reagent are also present on SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

ALT Names :

SV40 T Antigen (Ab-1) Mouse mAb (PAb419)

Immunogen :

the N-terminal domain of SV40 large and small T-antigen

Specificity :

Recognizes the ~94 kDa SV40 large T antigen and the ~20.5 kDa SV40 small T antigen.

Package Size :

100 ug

Uses :

WB, IF, IP

Storage :

Do not freeze