Fibroblast Antigen Mouse mAb (AS02) | EMD Millipore CP28-200UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Fibroblast Antigen Mouse mAb (AS02)

catalog :

CP28-200UG

quantity :

200 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 1

Reference
Hegarat N, Vesely C, Vinod P, Ocasio C, Peter N, Gannon J, et al. PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit. PLoS Genet. 2014;10:e1004004 pubmed publisher

product information

Catalog Number :

CP28-200UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Fibroblast Antigen Mouse mAb (AS02)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7070 (Hu), 21838 (Ms), 24832 (Rt)

Host Name :

Clone :

AS02

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Fibroblast Antigen Mouse mAb (AS02)

Cross Reactivity :

Human, Monkey

Background :

The ability to distinguish fibroblast contamination in cell cutures and tissues is an important biological problem. Identification of fibroblastic components of cells and tissues is also useful to determine the potential fibroblastic origin of tumors. The ability to specifically detect fibroblasts in tissue culture samples and in tissue samples in situ is often difficult. One of the chief problems has been the identification of a protein which is specific to fibroblasts and not shared by other cell types such as endothelial cells and chondrocytes. Most fibroblast specific reagents show some cross reactivity with monocytes/macrophages and smooth muscle cells. Currently, the most commonly used approach has been to use antibodies to proline-4-hydroxylase, a protein involved in the synthesis of collagen. However, proline-4-hydroxylase is present in all cells which make collagen, not just fibroblasts.

ALT Names :

CD7, CD90, FLJ33325, LOC94105, T25, Thy-1.2, Thy1.1, Thymus cell antigen 1, theta, Thy-1 cell surface antigen

Immunogen :

human fibroblasts

Specificity :

Recognizes the ~30-31 kDa fibroblast antigen (CD90/Thy-1) under non-reducing conditions.

Package Size :

200 ug

Uses :

FC, IH, WB, IF, IP