Integrin beta1 Mouse mAb (4B7) | EMD Millipore CP26-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin beta1 Mouse mAb (4B7)

catalog :

CP26-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation

product information

Catalog Number :

CP26-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Integrin beta1 Mouse mAb (4B7)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3688 (Hu), 16412 (Ms), 24511 (Rt)

Host Name :

Clone :

4B7

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin beta1 Mouse mAb (4B7)

Cross Reactivity :

Human

Background :

The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Expressed on essentially all cells as an alpha-beta dimeric protein, alterations in the integrin structure leading to changes in adhesive properties have important implications for tumor invasiveness and progression. The majority of the protein is found in the globular extracellular domain with the intracellular domain only composed of 60 amino acids or less. The beta 1 integrin is found widely distributed and is one of the subunits composing the major fibronectin receptor (FNR) along with the alpha 5 integrin. The beta 1 integrin has been shown to have a direct as well as a regulatory role in ligand binding and subsequent signal transduction.

ALT Names :

BETA1 INTEGRIN, BETA1 INTEGRIN RECEPTOR, CD29, CD29 antigen, FNRB, GPIIA, INTEGRIN BETA 1, INTEGRIN BETA 1 RECEPTOR, INTEGRIN BETA 1C, VLA-BETA, VLAB, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Immunogen :

recombinant, human beta1 integrin

Specificity :

Recognizes the beta1 integrin subunit.

Package Size :

100 ug

Uses :

IH, IF, IP, NEUT, IH(P)

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.