Collagen Type II (Ab-1) Mouse mAb (II-4C11) | EMD Millipore CP18-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Collagen Type II (Ab-1) Mouse mAb (II-4C11)

catalog :

CP18-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; domestic rabbit; 1:300	Zhang J, Wang J. Kartogenin induces cartilage-like tissue formation in tendon-bone junction. Bone Res. 2014;2: pubmed
	Huang H, Zhang X, Hu X, Shao Z, Zhu J, Dai L, et al. A functional biphasic biomaterial homing mesenchymal stem cells for inÂ vivo cartilage regeneration. Biomaterials. 2014;35:9608-19 pubmed publisher

product information

Catalog Number :

CP18-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Collagen Type II (Ab-1) Mouse mAb (II-4C11)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

1280 (Hu), 12824 (Ms), 25412 (Rt)

Host Name :

Clone :

II-4C11

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Collagen Type II (Ab-1) Mouse mAb (II-4C11)

Cross Reactivity :

Bovine, Human, Rabbit, Rat

Background :

Collagens are the major fibrous structural elements of cartilage, tendon, skin, bone, lung and blood vessels. Their function is to hold cells together and thereby form discrete tissues. Collagens form insoluble fibers that have a high intrinsic tensile strength. Structurally, the collagens are composed of three polypeptide chains, alphachains, which exist as three distinct subclasses each of which in turn is made up of numerous subtypes. Type II collagen is a major component of cartilage. It is translated as a pro-form which is then processed to yield the mature protein. Collagen II can also be expressed in two different forms, IIA and IIB, as a result of alternate splicing involving the inclusion of exon. The protein is synthesized primarily by chondrocytes and by certain cells in the eye, and exists as a trimer of alpha1(II) chains. Mutations in collagen II have been documented in chondrodysplasias and ostoarthrosis.

ALT Names :

ANFH, AOM, CG2A1A, COL11A3, COL2, Col2a, Collagen type II, COLLAGEN TYPE II ALPHA, Collagen type iia, COLLII, Del1, Dmm, MGC131516, MGC90638, SEDC, TYPE II COLLAGEN, collagen, type II, alpha 1

Immunogen :

purified collagen type II

Specificity :

Recognizes the ~130 kDa type II collagen protein.

Package Size :

100 ug

Uses :

IH, WB, IH(P)

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.