Integrin alpha3 Mouse mAb (P1B5) | EMD Millipore CP11L-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin alpha3 Mouse mAb (P1B5)

catalog :

CP11L-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 6	An X, Zhao Z, Luo Y, Zhang R, Tang X, Hao D, et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget. 2016;7:24719-33 pubmed publisher

product information

Catalog Number :

CP11L-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Integrin alpha3 Mouse mAb (P1B5)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3675 (Hu), 16400 (Ms), 360606 (Rt)

Host Name :

Clone :

P1B5

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Integrin alpha3 Mouse mAb (P1B5)

Cross Reactivity :

Human

Background :

The integrins are a family of cell surface glycoproteins that mediate both cell-cell adhesion and cell-substratum interactions. They are heterodimers consisting of noncovalently associated and subunits. Recently, it has been shown that there are six distinct subunits, and that some subunits may be associated with more than one betachain. The beta1 or VLA family of integrins has the largest number of members and share the common beta1 subunit. Studies have indicated that different integrins function in various combinations to mediate cell adhesion in different tissues. The alpha3/beta1 integrin, also termed VLA3 or CD49c, has been shown to interact primarily with secreted, laminin-containing extracellular matrix.

ALT Names :

Alpha3 integrin, CD49C, Galactoprotein B3, GAP-B3, INTEGRIN ALPHA 3, Itga3 (predicted), MSK18, VCA-2, VL3A, VLA-3 alpha chain, VLA3a, integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

Immunogen :

human mononuclear cells

Specificity :

Recognizes the alpha3 integrin subunit.

Package Size :

100 ug

Uses :

FUNC, FC, IF, IP

Storage :

We recommend resuspending the lyophilized antibody with sterile PBS, pH 7.4, or sterile 20 mM Tris-saline (20 mM Tris containing 0.15 M NaCl), pH 7.4, to yield a final concentration of 100 ug/ml; product will be more stable if 0.1% sodium azide is included (do not add azide if antibody is to be used with viable cells). Lyophilized antibody should be resuspended at 4°C with occasional gentle mixing for at least 2 h. Following reconstitution, refrigerate (4°C) for short-term storage (with azide) or aliquot and freeze (-20°C) for short-term storage.