alpha-Tubulin Mouse mAb (DM1A) | EMD Millipore CP06-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

alpha-Tubulin Mouse mAb (DM1A)

catalog :

CP06-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 22

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 1c	Rodriguez Gil J, Watkins Chow D, Baxter L, Elliot G, Harper U, Wincovitch S, et al. Genetic background modifies phenotypic severity and longevity in a mouse model of Niemann-Pick disease type C1. Dis Model Mech. 2020;13: pubmed publisher
western blot; human; 1:3000; loading ...; fig s3c	Fregni G, Quinodoz M, Möller E, Vuille J, Galland S, Fusco C, et al. Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis. EBioMedicine. 2018;29:128-145 pubmed publisher
western blot; human; loading ...; fig 3c	Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed publisher
western blot; human; fig 1	Sundararaman A, Amirtham U, Rangarajan A. Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation. J Biol Chem. 2016;291:14410-29 pubmed publisher
western blot; human; 1:5000; fig 1	Seip K, Fleten K, Barkovskaya A, Nygaard V, Haugen M, EngesÃ¦ter B, et al. Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors. Oncotarget. 2016;7:19997-20015 pubmed publisher
western blot; mouse; 1:5000; fig s1	Walter M, Teissandier A, PÃ©rez Palacios R, Bourc his D. An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. elife. 2016;5: pubmed publisher
western blot; human; fig 6	Mehraein Ghomi F, Church D, Schreiber C, Weichmann A, Basu H, Wilding G. Inhibitor of p52 NF-ÎºB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81). Genes Cancer. 2015;6:428-44 pubmed
western blot; human; fig 2	Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
western blot; human; 1:5000; fig 2 western blot; mouse; 1:5000; fig 2	Lee S, Won J, Yang J, Lee J, Kim S, Lee E, et al. AKAP6 inhibition impairs myoblast differentiation and muscle regeneration: Positive loop between AKAP6 and myogenin. Sci Rep. 2015;5:16523 pubmed publisher
immunocytochemistry; human; fig 4 western blot; human; fig 3	Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90Î± chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed publisher
western blot; human; 1:1000; fig 4	Habiger C, JÃ¤ger G, Walter M, Iftner T, Stubenrauch F. Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins. J Virol. 2016;90:694-704 pubmed publisher
western blot; human; fig 2	Ma Q, Hu Q, Xu R, Zhen X, Wang G. Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1. Acta Pharmacol Sin. 2015;36:966-75 pubmed publisher
western blot; human; fig 1	Schipany K, Rosner M, Ionce L, HengstschlÃ¤ger M, Kovacic B. eIF3 controls cell size independently of S6K1-activity. Oncotarget. 2015;6:24361-75 pubmed
western blot; human; fig 2	Riz I, Hawley T, Hawley R. KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models. Oncotarget. 2015;6:14814-31 pubmed
immunocytochemistry; human; 1:1000; fig 3 western blot; human; fig 3	O Callaghan K, Palagano E, Butini S, Campiani G, Williams D, Zisterer D, et al. Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines. Mol Med Rep. 2015;12:3748-3754 pubmed publisher
western blot; human; fig 2a	Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed publisher
western blot; human; 1:1000; fig 1	Kawasaki Y, Ishigami S, Arigami T, Uenosono Y, Yanagita S, Uchikado Y, et al. Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer. BMC Cancer. 2015;15:5 pubmed publisher
	LeBlanc M, Saez Torres K, Cano I, Hu Z, Saint Geniez M, Ng Y, et al. Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity. FASEB J. 2019;:fj201900011R pubmed publisher
	Lim S, Hermance N, Mudianto T, Mustaly H, Mauricio I, Vittoria M, et al. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nat Commun. 2019;10:1547 pubmed publisher
	Yang J, Platt L, Maity B, Ahlers K, Luo Z, Lin Z, et al. RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation. Oncotarget. 2016;7:69159-69172 pubmed publisher
	Zhao Y, Kumbrink J, Lin B, Bouton A, Yang S, Toselli P, et al. Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression. Carcinogenesis. 2013;34:2880-90 pubmed publisher
	Panigrahi A, Zhang N, Mao Q, Pati D. Calpain-1 cleaves Rad21 to promote sister chromatid separation. Mol Cell Biol. 2011;31:4335-47 pubmed publisher

product information

Catalog Number :

CP06-100UG

Category :

Antibodies

Subcategory :

Neuroscience

Product Name :

Anti-alpha-Tubulin Mouse mAb (DM1A)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7846 (Hu), 22142 (Ms), 64158 (Rt)

Host Name :

Clone :

DM1A

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-alpha-Tubulin Mouse mAb (DM1A)

Cross Reactivity :

Chicken, Gerbil, Human, Mouse, Rat

Background :

Cytoskeletal proteins are found in highly organized arrays within the cytoplasm of higher eukaryotic cells. These proteins are intimately involved in functions such as cell and intracellular organelle movement, maintenance of cell shape, and endocytosis. The cytoskeleton of most eukaryotic cells is comprised of at least three fibrous systems each with accessory proteins: the microfilaments, composed of actin; the microfibrils, composed of tubulin; and the intermediate filaments composed of vimentin. Monoclonal antibodies have been used to study the components of the cytoskeleton and their intracellular location, changes in the expression of these elements during differentiation, and the function of the cytoskeleton in living cells by microinjection of the antibodies.

ALT Names :

Alpha tubulin, Alpha tubulin isotype M alpha 1, Alpha1 tubulin, B-ALPHA-1, FLJ25113, LIS3, MGC102097, MGC102098, MGC102099, T-Alpha1 Tubulin, TRAF interacting, Tuba-1, Tuba2, TUBA3, Tubulin, TUBULIN ALPHA 3, tubulin, alpha 1a

Immunogen :

native chick brain microtubules

Specificity :

Recognizes the ~60 kDa tubulin protein.

Package Size :

100 ug

Uses :

WB, IF

Storage :

Do not freeze