Actin (Ab-1) Mouse mAb (JLA20) | EMD Millipore CP01-1EA product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Actin (Ab-1) Mouse mAb (JLA20)

catalog :

CP01-1EA

quantity :

1 ea

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:5000; loading ...; fig 3f	Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed publisher
western blot; human; fig 1 western blot; mouse; fig 5	Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed publisher
western blot; human; fig 2	Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
western blot; mouse; 1:5000; fig 1	Matzkin M, Miquet J, Fang Y, Hill C, Turyn D, Calandra R, et al. Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes. Aging (Albany NY). 2016;8:95-110 pubmed
western blot; human; fig 1	Dave J, Abbey C, Duran C, Seo H, Johnson G, Bayless K. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. J Cell Sci. 2016;129:743-56 pubmed publisher
western blot; human; fig s4	Orthwein A, Noordermeer S, Wilson M, Landry S, Enchev R, Sherker A, et al. A mechanism for the suppression of homologous recombination in G1 cells. Nature. 2015;528:422-6 pubmed publisher
western blot; human; 1:500; fig 7 western blot; mouse; 1:500; fig 3	MartÃnez A, SesÃ© M, Losa J, Robichaud N, Sonenberg N, Aasen T, et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS ONE. 2015;10:e0123352 pubmed publisher
western blot; human; 1:5000	Hamdi A, Lesnard A, Suzanne P, Robert T, Miteva M, Pellerano M, et al. Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions. Chembiochem. 2015;16:432-9 pubmed publisher
	Wang S, Celic I, Choi S, Riccomagno M, Wang Q, Sun L, et al. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014;34:12745-61 pubmed publisher

product information

Catalog Number :

CP01-1EA

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Actin (Ab-1) Mouse mAb (JLA20)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

58 (Hu), 11459 11465 (Ms), 29437 287876 (Rt)

Host Name :

Clone :

JLA20

Conjugate :

Diluted Ascites

Isotype :

IgM

Product Description :

Anti-Actin (Ab-1) Mouse mAb (JLA20)

Cross Reactivity :

A Broad Range Of Species

Background :

Cytoskeletal proteins are found in highly organized arrays within the cytoplasm of higher eukaryotic cells. These proteins are intimately involved in functions such as cell and intracellular organelle movement, maintenance of cell shape and endocytosis. The cytoskeleton of most eukaryotic cells is comprised of at least three fibrous systems each with accessory proteins: the microfilaments, composed of actin; the microfibrils, composed of tubulin; and the intermediate filaments composed of vimentin. Monoclonal antibodies have been used to study the components of the cytoskeleton and their intracellular location, changes in the expression of these elements during differentiation, and the function of the cytoskeleton in living cells by microinjection of the antibodies.

ALT Names :

ACTA, Acta-2, Acts, Actsk-1, ALPHA SKELETAL ACTIN, ALPHA1 ACTIN, ASMA, CFTD, CFTD1, CFTDM, Fetal isoform of skeletal alpha-actin, G-actin, MPFD, NEM1, NEM2, NEM3, SKA, SKELETAL ALPHA-ACTIN, SKELETAL MUSCLE ACTIN, actin, alpha 1, skeletal muscle

Immunogen :

chicken cytoskeletal proteins

Specificity :

Recognizes the ~42 kDa alpha-, beta- and ɣ-isoforms of actin.

Package Size :

1 ea

Uses :

WB, IF

Storage :

Following initial thaw, aliquot ascites and freeze (-20°C).