Cdh1 (Ab-2) Mouse mAb (DH01) | EMD Millipore CC43-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cdh1 (Ab-2) Mouse mAb (DH01)

catalog :

CC43-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, immunohistochemistry - paraffin section

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1b	Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed publisher
immunohistochemistry - paraffin section; human; fig 3 immunoprecipitation; human; 1:500; fig 3 western blot; human; 1:1000; fig 1	Pavlides S, Lecanda J, Daubriac J, Pandya U, Gama P, Blank S, et al. TGF-Î² activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth. Cell Cycle. 2016;15:931-47 pubmed publisher
western blot; human; 1:200; fig 6	Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher
western blot; mouse; fig 5a	Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, et al. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015;35:3657-68 pubmed publisher

product information

Catalog Number :

CC43-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Cdh1 (Ab-2) Mouse mAb (DH01)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

999 (Hu), 12550 (Ms), 83502 (Rt)

Host Name :

Clone :

DH01

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Cdh1 (Ab-2) Mouse mAb (DH01)

Cross Reactivity :

Human

Background :

Cdh1, a homolog of the yeast Cdc20, is a ~55 kDa protein required for the degradation of anaphase-promoting complex (APC)-dependent proteolysis. Cdh1 acts as a limiting, substrate-specific activator of APC-dependent proteolysis and it is required for the degradation of APC substrates such as Clb2 and Ase1. Cdh1 plays an important role in mitotic regulation.

ALT Names :

AA960649, Arc-1, Cadherin 1, CD324, CDHE, CSEIL, E-CADHERIN, E-CADHERIN 120 KDA, ECAD, L-CAM, MGC107495, Um, UVO, uvomorulin, cadherin 1, type 1, E-cadherin (epithelial)

Immunogen :

recombinant human Cdh1 protein

Specificity :

Recognizes the ~55 kDA Cdh1 protein.

Package Size :

100 ug

Uses :

WB, IP

Storage :

Do not freeze