CD49e Antibody, clone SAM-1 | EMD Millipore CBL497 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD49e Antibody, clone SAM-1

catalog :

CBL497

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SAM-1

The same clone is also sold as:

Santa Cruz Biotechnology: sc-52595
Abcam: ab6131
Beckman Coulter: IM0771, IM1854U
Invitrogen: 13-2600

reactivity :

human

application :

immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; 1:200; fig 5	MarkoviÄ‡ Lipkovski J, Å½ivotiÄ‡ M, MÃ¼ller C, Tampe B, Ä†iroviÄ‡ S, VjeÅ¡tica J, et al. Variable Expression of Neural Cell Adhesion Molecule Isoforms in Renal Tissue: Possible Role in Incipient Renal Fibrosis. PLoS ONE. 2015;10:e0137028 pubmed publisher
immunocytochemistry; human	Jakubowski P, Calvete J, Eble J, Lazarovici P, Marcinkiewicz C. Identification of inhibitors of ?2?1 integrin, members of C-lectin type proteins, in Echis sochureki venom. Toxicol Appl Pharmacol. 2013;269:34-42 pubmed publisher
	Morjen M, HonorÃ© S, Bazaa A, Abdelkafi Koubaa Z, Ellafi A, Mabrouk K, et al. PIVL, a snake venom Kunitz-type serine protease inhibitor, inhibits in vitro and in vivo angiogenesis. Microvasc Res. 2014;95:149-56 pubmed publisher
	Hanson A, Gambill J, Phomakay V, Staten C, Kelley M. 9-cis-retinoic Acid and troglitazone impacts cellular adhesion, proliferation, and integrin expression in K562 cells. PLoS ONE. 2014;9:e93005 pubmed publisher
	Pochec E, Janik M, Hoja Łukowicz D, Link Lenczowski P, Przybyło M, Litynska A. Expression of integrins ?3?1 and ?5?1 and GlcNAc ?1,6 glycan branching influences metastatic melanoma cell migration on fibronectin. Eur J Cell Biol. 2013;92:355-62 pubmed publisher
	Canonici A, Pellegrino E, Siret C, Terciolo C, Czerucka D, Bastonero S, et al. Saccharomyces boulardii improves intestinal epithelial cell restitution by inhibiting ?v?5 integrin activation state. PLoS ONE. 2012;7:e45047 pubmed publisher
	Chen C, Lu D, Yeh M, Shiau C, Chiang C. Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells. Int J Nanomedicine. 2011;6:2567-80 pubmed publisher
	Zaric J, Joseph J, Tercier S, Sengstag T, Ponsonnet L, Delorenzi M, et al. Identification of MAGI1 as a tumor-suppressor protein induced by cyclooxygenase-2 inhibitors in colorectal cancer cells. Oncogene. 2012;31:48-59 pubmed publisher
	Neal C, McKeithen D, Odero Marah V. Snail negatively regulates cell adhesion to extracellular matrix and integrin expression via the MAPK pathway in prostate cancer cells. Cell Adh Migr. 2011;5:249-57 pubmed
	Malara A, Gruppi C, Rebuzzini P, Visai L, Perotti C, Moratti R, et al. Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A. Blood. 2011;117:2476-83 pubmed publisher
	Lowin T, Straub R, Neumann E, Bosserhoff A, Vogel C, Moissl C, et al. Glucocorticoids increase alpha5 integrin expression and adhesion of synovial fibroblasts but inhibit ERK signaling, migration, and cartilage invasion. Arthritis Rheum. 2009;60:3623-32 pubmed publisher
	Slack Davis J, Atkins K, Harrer C, Hershey E, Conaway M. Vascular cell adhesion molecule-1 is a regulator of ovarian cancer peritoneal metastasis. Cancer Res. 2009;69:1469-76 pubmed publisher
	Fiorilli P, Partridge D, Staniszewska I, Wang J, Grabacka M, So K, et al. Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferation. Lab Invest. 2008;88:1143-56 pubmed publisher
	Kawajiri H, Yashiro M, Shinto O, Nakamura K, Tendo M, Takemura S, et al. A novel transforming growth factor beta receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma. Clin Cancer Res. 2008;14:2850-60 pubmed publisher
	Przybyło M, Pochec E, Link Lenczowski P, Litynska A. Beta1-6 branching of cell surface glycoproteins may contribute to uveal melanoma progression by up-regulating cell motility. Mol Vis. 2008;14:625-36 pubmed
	Huang J, Bridges L, White J. Selective modulation of integrin-mediated cell migration by distinct ADAM family members. Mol Biol Cell. 2005;16:4982-91 pubmed

product information

Catalog Number :

CBL497

Subcategory :

Cell Structure

Product Name :

Anti-CD49e Antibody, clone SAM-1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P08648

Host Name :

Mouse

Antigen :

CD49e

Clone :

SAM-1

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-CD49e Antibody, clone SAM-1

Cross Reactivity :

Human

ALT Names :

Integrin alpha5

Immunogen :

U937 cells

Specificity :

The monoclonal antibody is directed against the CD49e antigen (GPIc or VLA-5 alpha chain), which can form distinct complexes with either the CD29 antigen (GP IIa or VLA beta chain), resulting in the VLA-5 (alpha5 beta1) complex which is expressed on human platelets. The monoclonal antibody reacts with platelets and monocytes and also weakly with T cells and granulocytes. It also reacts with various cell types of non-haemopoietic origin. FUSION PARTNER: SP2/0 myeloma cell line

Package Size :

100 µg

Uses :

Flow Cytometry;Immunofluorescence;Affects Function

Storage :

Maintain at 2-8°C for up to 12 months from date of receipt.