This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Tubulin β-III Antibody, clone TU-20, Alexa Fluor®488 Conjugated
catalog :
CBL412X
quantity :
40 µL
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
TU-20

The same clone is also sold as:
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; fig 1
Zhang Q, Dan J, Wang H, Guo R, Mao J, Fu H, et al. Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells. Sci Rep. 2016;6:19852 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig S6
Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, et al. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology. PLoS ONE. 2015;10:e0125697 pubmed publisher
  • immunocytochemistry; rat; 1:200
Dixon A, Philbert M. Morphometric assessment of toxicant induced neuronal degeneration in full and restricted contact co-cultures of embryonic cortical rat neurons and astrocytes: using m-Dinitrobezene as a model neurotoxicant. Toxicol In Vitro. 2015;29:564-74 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:250
Sun F, Zhou K, Wang S, Liang P, Zhu M, Qiu J. Expression patterns of atrial natriuretic peptide and its receptors within the cochlear spiral ganglion of the postnatal rat. Hear Res. 2014;309:103-12 pubmed publisher
Dixon A, Horst E, Garcia J, Ndjouyep Yamaga P, Mehta G. Morphometric and computational assessments to evaluate neuron survival and maturation within compartmentalized microfluidic devices: The influence of design variation on diffusion-driven nutrient transport. Neurosci Lett. 2019;703:58-67 pubmed publisher
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, et al. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture. PLoS ONE. 2014;9:e112900 pubmed publisher
Molina Calavita M, Barnat M, Elias S, Aparicio E, Piel M, Humbert S. Mutant huntingtin affects cortical progenitor cell division and development of the mouse neocortex. J Neurosci. 2014;34:10034-40 pubmed publisher
De Felice C, Della Ragione F, Signorini C, Leoncini S, Pecorelli A, Ciccoli L, et al. Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome. Neurobiol Dis. 2014;68:66-77 pubmed publisher
Shang W, Zhang X, Zhang M, Fan Z, Sun Y, Han M, et al. The uptake mechanism and biocompatibility of graphene quantum dots with human neural stem cells. Nanoscale. 2014;6:5799-806 pubmed publisher
Alexiou G, Moschovi M, Stefanaki K, Panagopoulos D, Tsotra M, Siozos G, et al. Supratentorial ependymomas in children: Analysis of nine cases. J Pediatr Neurosci. 2013;8:15-8 pubmed publisher
Guo H, Zhao Z, Yang Q, Wang M, Bell R, Wang S, et al. An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway. J Neurosci. 2013;33:6181-90 pubmed publisher
Quach D, Oliveira Fernandes M, Gruner K, Tourtellotte W. A sympathetic neuron autonomous role for Egr3-mediated gene regulation in dendrite morphogenesis and target tissue innervation. J Neurosci. 2013;33:4570-83 pubmed publisher
Martineau M, Shi T, Puyal J, Knolhoff A, Dulong J, Gasnier B, et al. Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci. 2013;33:3413-23 pubmed publisher
Xu X, Lei Y, Luo J, Wang J, Zhang S, Yang X, et al. Prevention of ?-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events. Stem Cell Res. 2013;10:213-27 pubmed publisher
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
Keeve P, Dittmar T, Gassmann G, Grimm W, Niggemann B, Friedmann A. Characterization and analysis of migration patterns of dentospheres derived from periodontal tissue and the palate. J Periodontal Res. 2013;48:276-85 pubmed publisher
Teramura T, Onodera Y, Takehara T, Frampton J, Matsuoka T, Ito S, et al. Induction of functional mesenchymal stem cells from rabbit embryonic stem cells by exposure to severe hypoxic conditions. Cell Transplant. 2013;22:309-29 pubmed publisher
Ozturk G, Cengiz N, Erdogan E, Him A, Oğuz E, Yenidünya E, et al. Two distinct types of dying back axonal degeneration in vitro. Neuropathol Appl Neurobiol. 2013;39:362-76 pubmed publisher
Tao J, Qiu B, Zhang D, Wang Y. Expression levels of Fas/Fas-L mRNA in human brain glioma stem cells. Mol Med Rep. 2012;5:1202-6 pubmed publisher
Munier M, Law F, Meduri G, Le Menuet D, Lombes M. Mineralocorticoid receptor overexpression facilitates differentiation and promotes survival of embryonic stem cell-derived neurons. Endocrinology. 2012;153:1330-40 pubmed publisher
Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, et al. Girdin maintains the stemness of glioblastoma stem cells. Oncogene. 2012;31:2715-24 pubmed publisher
Jaako K, Aonurm Helm A, Kalda A, Anier K, Zharkovsky T, Shastin D, et al. Repeated citalopram administration counteracts kainic acid-induced spreading of PSA-NCAM-immunoreactive cells and loss of reelin in the adult mouse hippocampus. Eur J Pharmacol. 2011;666:61-71 pubmed publisher
Qiu B, Zhang D, Wang C, Tao J, Tie X, Qiao Y, et al. IL-10 and TGF-?2 are overexpressed in tumor spheres cultured from human gliomas. Mol Biol Rep. 2011;38:3585-91 pubmed publisher
Hasegawa K, Zhang P, Wei Z, Pomeroy J, Lu W, Pera M. Comparison of reprogramming efficiency between transduction of reprogramming factors, cell-cell fusion, and cytoplast fusion. Stem Cells. 2010;28:1338-48 pubmed publisher
Walton J. Brain lesions comprised of aluminum-rich cells that lack microtubules may be associated with the cognitive deficit of Alzheimer's disease. Neurotoxicology. 2009;30:1059-69 pubmed publisher
Tomé M, Lindsay S, Riddell J, Barnett S. Identification of nonepithelial multipotent cells in the embryonic olfactory mucosa. Stem Cells. 2009;27:2196-208 pubmed publisher
Hill E, Woehrling E, Prince M, Coleman M. Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing. Toxicology. 2008;249:243-50 pubmed publisher
Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, et al. Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. J Neurosci. 2008;28:4250-60 pubmed publisher
product information
Catalog Number :
CBL412X
Subcategory :
Neuroscience
Product Name :
Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor®488 Conjugated
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q13509
Host Name :
Mouse
Antigen :
Tubulin β-III
Clone :
TU-20
Conjugate :
Purified
Isotype :
IgG1
Product Description :
Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor®488 Conjugated
Cross Reactivity :
Bovine;Human;Primate;Mouse;Pig;Rat
Background :
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
ALT Names :
Tubulin beta-4;Tubulin beta-III ;tubulin, beta 3;tubulin, beta, 4
Specificity :
This antibody reacts with the C-terminus of the beta-III isoform of tubulin, which is known to be neuron specific. Does not identify beta tubulin found in glial cells.
Package Size :
40 µL
Uses :
Immunocytochemistry;Immunofluorescence;Western Blotting;Immunohistochemistry;Immunoprecipitation
Storage :
Stable for 6 months at 2-8°C from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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