Filamin Antibody, clone PM6/317 | EMD Millipore CBL228 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Filamin Antibody, clone PM6/317

catalog :

CBL228

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PM6/317

The same clone is also sold as:

LifeSpan Biosciences: LS-C85122
Santa Cruz Biotechnology: sc-58764
MilliporeSigma: F6682

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1a	Bhalla M, Van Ngo H, Gyanwali G, Ireton K. The Host Scaffolding Protein Filamin A and the Exocyst Complex Control Exocytosis during InlB-Mediated Entry of Listeria monocytogenes. Infect Immun. 2019;87: pubmed publisher

product information

Catalog Number :

CBL228

Subcategory :

Cell Structure

Product Name :

Anti-Filamin Antibody, clone PM6/317

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P21333

Host Name :

Mouse

Antigen :

Filamin

Clone :

PM6/317

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Filamin Antibody, clone PM6/317

Cross Reactivity :

Human;Guinea Pig;Chicken;Rabbit;Rat

Background :

Filamin is a structural protein that forms flexible cross-links between two actin filaments. Filamin is a homodimer of polypeptide chains each joined to the other at one end with an actin binding site ath the other. It is present in smooth muscle, fibroblasts, platelets and lymphocytes.

ALT Names :

Alpha-Filamin; Filamin I; Endothelial Actin-binding Protein; ABP-280; Nonmuscle Filamin

Immunogen :

Platelet filamin

Specificity :

Recognizes unprocessed, full length Human filamin (actin-binding protein; 270-280 kDa) as well as the 190 kDa N-terminal calpain cleavage fragment of filamin (Aakhus, 1992). Following induction of apoptosis in U937 cells, the antibody recognizes 170, 150, and 120 kDa N-terminal cleavage fragments of the full-length form presumably resulting from cleavage by activated caspase-3 (Umeda, 2001).

Package Size :

100 µg

Uses :

Western Blotting;Immunohistochemistry;Immunohistochemistry (Paraffin)

Storage :

For use within 1 month of purchase store at +4°C; for long term storage aliquot antibody into small volumes and store at -20°C.