DNA Antibody, clone AC-30-10 | EMD Millipore CBL186 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

DNA Antibody, clone AC-30-10

catalog :

CBL186

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AC-30-10

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; fig 1e	Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
immunocytochemistry; human; 1:1000; fig 2c	Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed publisher
immunocytochemistry; mouse; fig 1	West A, Khoury Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
immunocytochemistry; human	Li S, Guo J, Ying Z, Chen S, Yang L, Chen K, et al. Valproic acid-induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening-dependent apoptotic sensitivity in an induced pluripotent stem cell model. Hepatology. 2015;61:1730-9 pubmed publisher
	Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
	Bonora M, Ito K, Morganti C, Pinton P, Ito K. Membrane-potential compensation reveals mitochondrial volume expansion during HSC commitment. Exp Hematol. 2018;68:30-37.e1 pubmed publisher
	Yang K, Huang R, Fujihira H, Suzuki T, Yan N. N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1. J Exp Med. 2018;215:2600-2616 pubmed publisher
	Torralba D, Baixauli F, Villarroya Beltri C, Fernandez Delgado I, Latorre Pellicer A, Acin Perez R, et al. Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts. Nat Commun. 2018;9:2658 pubmed publisher
	Vaites L, Paulo J, Huttlin E, Harper J. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux. Mol Cell Biol. 2018;38: pubmed publisher
	Tsai P, Papakyrikos A, Hsieh C, Wang X. Drosophila MIC60/mitofilin conducts dual roles in mitochondrial motility and crista structure. Mol Biol Cell. 2017;28:3471-3479 pubmed publisher
	Hu Z, Leppla S, Li B, Elkins C. Antibodies specific for nucleic acids and applications in genomic detection and clinical diagnostics. Expert Rev Mol Diagn. 2014;14:895-916 pubmed publisher
	Wang Y, Marinov G, Wold B, Chan D. Genome-wide analysis reveals coating of the mitochondrial genome by TFAM. PLoS ONE. 2013;8:e74513 pubmed publisher
	Stradalova V, Gaplovska Kysela K, Hozak P. Ultrastructural and nuclear antigen preservation after high-pressure freezing/freeze-substitution and low-temperature LR White embedding of HeLa cells. Histochem Cell Biol. 2008;130:1047-52 pubmed publisher
	Lee H, Greeley G, Englander E. Sustained hypoxia modulates mitochondrial DNA content in the neonatal rat brain. Free Radic Biol Med. 2008;44:807-14 pubmed

product information

Catalog Number :

CBL186

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-DNA Antibody, clone AC-30-10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

DNA

Clone :

AC-30-10

Conjugate :

Purified

Isotype :

IgM

Product Description :

Anti-DNA Antibody, clone AC-30-10

Cross Reactivity :

All

ALT Names :

Deoxyribonucleic acid

Specificity :

This antibody reacts with native denatured DNA extracted from various organisms: mouse DNA, calf thymus DNA, M13 DNA, SV-40 DNA and several plasmids. It also reacts with synthetic DNA of different base compositions: poly dAT-poly dAT, poly dAT. DNA-containing structures such as chromatin in diverse tissues from several species as well as in diverse cell lines such as XLKE-A6 (Xenopus), RVF-SMC (rat kangaroo) and HeLa (human) are also recognized.

Package Size :

50 µg

Uses :

Immunofluorescence;Immunohistochemistry (Paraffin)

Storage :

Maintain at 2-8°C for up to 12 months from date of receipt.