CD117 Antibody, clone ACK2 | EMD Millipore CBL1360 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD117 Antibody, clone ACK2

catalog :

CBL1360

quantity :

500 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

ACK2

The same clone is also sold as:

BioLegend: 135123, 135106, 135119, 135127, 135135, 135118, 135121, 135101, 135139, 135115, 135102, 135105, 135128, 135140, 135107, 135114, 135122, 135108, 135129, 135132, 135111, 135112, 135134, 135138, 135136, 135125, 135133, 135120, 135131, 135124
Novus Biologicals: NBP1-43359-0.1mg
Invitrogen: 61-1172-80, 16-1172-050, 14-1172-85, 12-1172-82, 62-1172-80, 62-1172-82, 17-1172-83, 16-1172-025, 56-1172-80, 16-1172-81, 46-1172-82, 46-1172-80, 16-1172-82, 47-1172-82, 17-1172-81, 14-1172-82, 56-1172-82, 67-1172-82, 14-1172-81, 25-1172-82, 61-1172-82, 16-1172-38, 67-1172-80, 12-1172-83, 47-1172-80, 16-1172-85, 17-1172-82
Abnova: MAB10952
LifeSpan Biosciences: LS-C107133
OriGene: TA320402
Bio X Cell: BE0293-50MG, BE0293-1MG, BE0293-100MG, BE0293-25MG, BE0293-5MG

reactivity :

mouse

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:250; fig 1b	Kondo J, Powell A, Wang Y, Musser M, Southard Smith E, Franklin J, et al. LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice. Gastroenterology. 2015;149:407-19.e8 pubmed publisher
western blot; mouse; 1:250; fig 4	Wang Y, Shi C, Lu Y, Poulin E, Franklin J, Coffey R. Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia. Am J Pathol. 2015;185:1123-34 pubmed publisher
immunohistochemistry; mouse; 1:250	Poulin E, Powell A, Wang Y, Li Y, Franklin J, Coffey R. Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine. Stem Cell Res. 2014;13:422-30 pubmed publisher
flow cytometry; mouse	Petrakova O, Terskikh V, Chernioglo E, Ashapkin V, Bragin E, Shtratnikova V, et al. Comparative analysis reveals similarities between cultured submandibular salivary gland cells and liver progenitor cells. Springerplus. 2014;3:183 pubmed publisher
	Sharma M, Braun R. Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis. Development. 2018;145: pubmed publisher
	Zhang C, Wang P, Liu D, Chen C, Zhao W, Chen X, et al. The molecular basis of the genesis of basal tone in internal anal sphincter. Nat Commun. 2016;7:11358 pubmed publisher
	Sun W, Wilhelmina Aalders T, Oosterwijk E. Identification of potential bladder progenitor cells in the trigone. Dev Biol. 2014;393:84-92 pubmed publisher
	Koh B, Roy R, Hollywood M, Thornbury K, McHale N, Sergeant G, et al. Platelet-derived growth factor receptor-? cells in mouse urinary bladder: a new class of interstitial cells. J Cell Mol Med. 2012;16:691-700 pubmed publisher
	Tan B, Lee M, Ruan R. Bone-marrow-derived cells that home to acoustic deafened cochlea preserved their hematopoietic identity. J Comp Neurol. 2008;509:167-79 pubmed publisher
	Tokuda M, Kadokawa Y, Kurahashi H, Marunouchi T. CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes. Biol Reprod. 2007;76:130-41 pubmed

product information

Catalog Number :

CBL1360

Subcategory :

Stem Cell Research

Product Name :

Anti-CD117 Antibody, clone ACK2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10721

Host Name :

Rat

Antigen :

CD117

Clone :

ACK2

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-CD117 Antibody, clone ACK2

Cross Reactivity :

Mouse

Background :

This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells.

ALT Names :

c-kit; SCF Receptor

Specificity :

Specifically recognizes mouse CD117, known as c-kit receptor, stem cell factor receptor and steel factor receptor.

Package Size :

500 µg

Uses :

Flow Cytometry;Immunohistochemistry;Immunoprecipitation;Affects Function;Western Blotting

Storage :

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.