Integrin beta1 Antibody, clone HM beta 1.1 | EMD Millipore CBL1348 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin beta1 Antibody, clone HM beta 1.1

catalog :

CBL1348

quantity :

100 μg

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

HM beta 1.1

The same clone is also sold as:

Bio-Rad: MCA2298FT, MCA2298A488T, MCA2298FB, MCA2298F, MCA2298PE, MCA2298A647, MCA2298A488, MCA2298EL, MCA2298A647T, MCA2298GA
LifeSpan Biosciences: LS-C44636, LS-C44635, LS-C44638, LS-C44639
Abcam: ab36219
Invitrogen: MA5-16707, MA1-81498, MA1-81468, MA5-16708
OriGene: SM2210PS, SM2210F, SM2210LE, SM2210R, SM2210FT, SM2210FX

reactivity :

human, mouse

application :

immunocytochemistry

citations: 1

Reference
Felgueiras H, Sommerfeld S, Murthy N, Kohn J, Migonney V. Poly(NaSS) functionalization modulates the conformation of fibronectin and collagen type I to enhance osteoblastic cell attachment onto Ti6Al4V. Langmuir. 2014;30:9477-83 pubmed publisher

product information

Catalog Number :

CBL1348

Subcategory :

Cell Structure

Product Name :

Anti-Integrin beta1 Antibody, clone HM beta 1.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09055

Host Name :

Hamster

Antigen :

Integrin beta1

Clone :

HM beta 1.1

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Integrin beta1 Antibody, clone HM beta 1.1

Cross Reactivity :

Human;Mouse

Background :

Integrin beta 1is also known as CD29. It is a transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits, forming the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions such as hemostasis, embryonic development, wound repair, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion.

ALT Names :

CD29 antigen;Fibronectin receptor subunit beta;Integrin VLA-4 subunit beta ;fibronectin receptor beta subunit;integrin VLA-4 beta subunit;integrin beta 1 ;integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Immunogen :

Purified mouse VLA-4 antigen

Package Size :

100 μg

Uses :

Immunocytochemistry

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.