PECAM-1 Antibody, clone 390 | EMD Millipore CBL1337 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PECAM-1 Antibody, clone 390

catalog :

CBL1337

quantity :

500 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

390

The same clone is also sold as:

LifeSpan Biosciences: LS-C350211, LS-C350220, LS-C350210, LS-C4937, LS-C196263, LS-C196262, LS-C350209, LS-C4925, LS-C106063, LS-C4931, LS-C84982, LS-C350208, LS-C350218, LS-C196264, LS-C86798, LS-C350212, LS-C4930, LS-C196261
Miltenyi Biotec: 130-119-562, 130-123-813, 130-102-902, 130-119-662, 130-119-653, 130-123-675, 130-102-375, 130-110-306, 130-110-407
MyBioSource: MBS673319
Invitrogen: 14-0311-85, 61-0311-80, 14-0311-82, 64-0311-82, 11-0311-81, 14-0311-81, 15-0311-82, 48-0311-82, 16-0311-38, 62-0311-80, 64-0311-80, 16-0311-050, 25-0311-82, 17-0311-82, A14716, 13-0311-85, 25-0311-81, 12-0311-82, 63-0311-82, 11-0311-82, 13-0311-81, 46-0311-80, 17-0311-80, 15-0311-80, 12-0311-83, 61-0311-82, 16-0311-025, 62-0311-82, 48-0311-80, A14715, 46-0311-82, 11-0311-85, RM5201, 13-0311-82, 12-0311-81, RM5228, 16-0311-85
BD Biosciences: 558738, 558736, 553708
OriGene: TA320444
BioLegend: 102444, 102414, 102417, 102401, 102430, 102418, 102425, 102429, 102422, 102437, 102435, 102405, 102440, 102416, 102423, 102406, 102402, 102439, 102419, 102451, 102415, 102432, 102424, 102408, 102407, 102409, 102420, 102427, 102445, 102448, 102446, 102434, 102410, 102447, 102433, 102421, 102413, 102449, 102443, 102404, 102441
Abnova: MAB5716, MAB5715, MAB3230, MAB5714, MAB5713, MAB5712

reactivity :

human, mouse

application :

immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 24

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; fig 2	Hobbs R, Batazzi A, Han M, Coulombe P. Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo. Oncogene. 2016;35:5653-5662 pubmed publisher
immunohistochemistry; mouse; fig s1d	Hobbs R, DePianto D, Jacob J, Han M, Chung B, Batazzi A, et al. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nat Genet. 2015;47:933-8 pubmed publisher
immunohistochemistry - frozen section; human; 10 ug/ml	Hu Y, Ru N, Xiao H, Chaturbedi A, Hoa N, Tian X, et al. Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity. PLoS ONE. 2013;8:e80898 pubmed publisher
	Huang L, Hong Z, Wu W, Xiong S, Zhong M, Gao X, et al. mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury. Immunity. 2020;52:475-486.e5 pubmed publisher
	Conti L, Lanzardo S, Iezzi M, Montone M, Bolli E, Brioschi C, et al. Optical imaging detection of microscopic mammary cancer in ErbB-2 transgenic mice through the DA364 probe binding ?v ?3 integrins. Contrast Media Mol Imaging. 2013;8:350-60 pubmed publisher
	Poduslo J, Hultman K, Curran G, Preboske G, Chamberlain R, Marjańska M, et al. Targeting vascular amyloid in arterioles of Alzheimer disease transgenic mice with amyloid ? protein antibody-coated nanoparticles. J Neuropathol Exp Neurol. 2011;70:653-61 pubmed publisher
	Hoffman R. Nestin-driven green fluorescent protein as an imaging marker for nascent blood vessels in mouse models of cancer. Methods Mol Biol. 2011;689:183-204 pubmed publisher
	Hamza L, Girardi T, Castelli S, Gargioli C, Cannata S, Patamia M, et al. Isolation and characterization of a myotoxin from the venom of Macrovipera lebetina transmediterranea. Toxicon. 2010;56:381-90 pubmed publisher
	Aki R, Amoh Y, Li L, Katsuoka K, Hoffman R. Nestin-expressing interfollicular blood vessel network contributes to skin transplant survival and wound healing. J Cell Biochem. 2010;110:80-6 pubmed publisher
	Dratviman Storobinsky O, Avraham Lubin B, Hasanreisoglu M, Goldenberg Cohen N. Effect of subconjuctival and intraocular bevacizumab injection on angiogenic gene expression levels in a mouse model of corneal neovascularization. Mol Vis. 2009;15:2326-38 pubmed
	Hoffman R. Dual-color imaging of tumor angiogenesis. Methods Mol Biol. 2009;515:45-61 pubmed publisher
	Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, et al. A color-coded orthotopic nude-mouse treatment model of brain-metastatic paralyzing spinal cord cancer that induces angiogenesis and neurogenesis. Cell Prolif. 2009;42:75-82 pubmed publisher
	Niclou S, Danzeisen C, Eikesdal H, Wiig H, Brons N, Poli A, et al. A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. FASEB J. 2008;22:3120-8 pubmed publisher
	Ji Y, Hayashi K, Amoh Y, Tsuji K, Yamauchi K, Yamamoto N, et al. The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. Anticancer Res. 2007;27:713-8 pubmed
	Hayashi K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Amoh Y, et al. Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. J Surg Res. 2007;140:165-70 pubmed
	Hoffman R, Yang M. Color-coded fluorescence imaging of tumor-host interactions. Nat Protoc. 2006;1:928-35 pubmed
	Amoh Y, Bouvet M, Li L, Tsuji K, Moossa A, Katsuoka K, et al. Visualization of nascent tumor angiogenesis in lung and liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP mice. Clin Exp Metastasis. 2006;23:315-22 pubmed
	Amoh Y, Nagakura C, Maitra A, Moossa A, Katsuoka K, Hoffman R, et al. Dual-color imaging of nascent angiogenesis and its inhibition in liver metastases of pancreatic cancer. Anticancer Res. 2006;26:3237-42 pubmed
	Amoh Y, Li L, Katsuoka K, Hoffman R. Chemotherapy targets the hair-follicle vascular network but not the stem cells. J Invest Dermatol. 2007;127:11-5 pubmed
	Wessells H, Teal T, Luttrell I, Sullivan C. Effect of endothelial cell-based iNOS gene transfer on cavernosal eNOS expression and mouse erectile responses. Int J Impot Res. 2006;18:438-45 pubmed
	Amoh Y, Li L, Tsuji K, Moossa A, Katsuoka K, Hoffman R, et al. Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine. J Surg Res. 2006;132:164-9 pubmed
	Amoh Y, Yang M, Li L, Reynoso J, Bouvet M, Moossa A, et al. Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis. Cancer Res. 2005;65:5352-7 pubmed
	Amoh Y, Li L, Yang M, Jiang P, Moossa A, Katsuoka K, et al. Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited by Doxorubicin. Cancer Res. 2005;65:2337-43 pubmed
	Mahendra G, Kumar S, Isayeva T, Mahasreshti P, Curiel D, Stockardt C, et al. Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor. Cancer Gene Ther. 2005;12:26-34 pubmed

product information

Catalog Number :

CBL1337

Subcategory :

Cell Structure

Product Name :

Anti-PECAM-1 Antibody, clone 390

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P16284

Host Name :

Rat

Antigen :

PECAM-1

Clone :

390

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-PECAM-1 Antibody, clone 390

Cross Reactivity :

Mouse

Background :

CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1) is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.

ALT Names :

CD31

Immunogen :

Mouse leukocyte cell line 32D

Specificity :

CBL1337 recognizes mouse PECAM-1, a 130-140 kDa type 1 integral membrane glycoprotein. This antibody has been shown to inhibit the aggregation of L cells transfected with a variant form of PECAM-1 (DeLisser, 1993).

Package Size :

500 µg

Uses :

Flow Cytometry;Immunohistochemistry;Immunoprecipitation;Affects Function

Storage :

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.