Thrombospondin (Ab-3) Mouse mAb (A6.1) | EMD Millipore BA24-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Thrombospondin (Ab-3) Mouse mAb (A6.1)

catalog :

BA24-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

product information

Catalog Number :

BA24-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-Thrombospondin (Ab-3) Mouse mAb (A6.1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7057 (Hu), 21825 (Ms), 445442 (Rt)

Host Name :

Clone :

A6.1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Thrombospondin (Ab-3) Mouse mAb (A6.1)

Cross Reactivity :

Bovine, Canine, Horse, Human, Porcine, Rat, Sheep

Background :

Thrombospondin (TSP) is a ~450 kDa glycoprotein synthesized by platelets, as well as by monocytes, macrophages, fibroblasts and endothelial cells. Although TSP is the major alpha-granule protein of human platelets, the concentration of the protein in circulating plasma is quite low. Upon stimulation of platelets, the TSP is expressed on the cell surface where it plays a role in platelet aggregation and other cell-cell interactions. Studies show that the platelet-monocyte association has been demonstrated to be mediated by the interaction of TSP on the platelet surface with a monocyte TSP receptor. The receptor has been identified immunologically as glycoprotein IV, also known as GPIIIb and CD36, a ~90 kDa membrane glycoprotein expressed on platelets, endothelial cells, erythrocytes, monocytes, and some human tumor cells lines but not on lymphocytes or granulocytes.

ALT Names :

tbsp1, THBS, THROMBOSPONDIN-1, TS-1, TSP, TSP-1, thrombospondin 1

Immunogen :

reduced and alkylated human thrombospondin

Specificity :

Recognizes the ~450 kDa (non-reduced) or the ~180 kDa (reduced) thrombospondin (TSP) protein.

Package Size :

100 ug

Uses :

FC, IH, WB, IF, NEUT

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.