A20 Mouse mAb (59A426) | EMD Millipore AM63-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

A20 Mouse mAb (59A426)

catalog :

AM63-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

Catalog Number :

AM63-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-A20 Mouse mAb (59A426)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

7128 (Hu), 21929 (Ms)

Host Name :

Clone :

59A426

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-A20 Mouse mAb (59A426)

Cross Reactivity :

Human

Background :

NF-kappaB (nuclear factor kappaB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The zinc finger protein A20 is a tumor necrosis factor and interleukin 1 (IL-1)-inducible protein that negatively regulates NF-kappaB gene expression by interferring with a novel TNF-induced and RIP- or TRAF2-mediated pathway that is different from the NIK-IkappaB kinase pathway. A20, an 70 kDa protein, is expressed at low levels in most organs, the highest expression levels being in lymphoid tissues.

ALT Names :

A20, MAD6, MGC104522, MGC138687, MGC138688, OTUD7C, TNF ALPHA-INDUCED PROTEIN 3, TNF-inducible early response, TNFA1P2, Tnfip3, tumor necrosis factor, alpha-induced protein 3

Immunogen :

full-length recombinant human A20 protein

Specificity :

Recognizes the ~70 kDa A20 protein.

Package Size :

100 ug

Uses :

WB, IP

Storage :

Following initial thaw, aliquot freeze (-20°C). Avoid repeated freeze-thaw.