Pericentrin Antibody | EMD Millipore ABT59 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Pericentrin Antibody

catalog :

ABT59

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; fig 3a	Hsieh W, Ramadesikan S, FEKETE D, Aguilar R. Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex. PLoS ONE. 2018;13:e0192635 pubmed publisher
western blot; human; loading ...; fig 2a	Wang Q, Tang Y, Xu Y, Xu S, Jiang Y, Dong Q, et al. The X-linked deubiquitinase USP9X is an integral component of centrosome. J Biol Chem. 2017;292:12874-12884 pubmed publisher
	Rezey A, Gerlach B, Wang R, Liao G, Tang D. Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma. Sci Rep. 2019;9:7555 pubmed publisher
	Markmiller S, Fulzele A, Higgins R, Leonard M, Yeo G, Bennett E. Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics. Cell Rep. 2019;27:1356-1363.e3 pubmed publisher
	Conte C, Baird M, Davidson M, Griffis E. Spindly is required for rapid migration of human cells. Biol Open. 2018;7: pubmed publisher

product information

Catalog Number :

ABT59

Subcategory :

Cell Structure

Product Name :

Anti-Pericentrin Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O95613

Host Name :

Rabbit

Antigen :

Pericentrin

Conjugate :

Affinity Purified

Product Description :

Anti-Pericentrin Antibody

Cross Reactivity :

Human

Background :

Pericentrin binds to calmodulin and is expressed in the centrosome that serves as a multifunctional scaffold for anchoring proteins and protein complexes. Evidence suggests that pericentrin plays a role in microtubule nucleation and spindle organization. Recent studies show pericentrin plays a role in Majewski/micorcephalic osteodysplastic primordial dwarfism type II (MOPDII) and Seckel Syndrome. Recent use in network modeling indicates a direct link between breast cancer susceptibility to centrosome defects. Pericentrin is a potential marker for centrosome defects in cancer and cancer progression, as centrosomal abonormalities in solid tumors are accompanied by increased pericentrin levels and defects in pericentrin organization.

ALT Names :

Pericentrin;Kendrin;Pericentrin-B

Immunogen :

KLH-conjugated linear peptide corresponding to human Pericentrin.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt