Spectrin beta chain Antibody, erythrocyte | EMD Millipore ABT185 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Spectrin beta chain Antibody, erythrocyte

catalog :

ABT185

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, Rhesus monkey

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Ijaz F, Hatanaka Y, Hatanaka T, Tsutsumi K, Iwaki T, Umemura K, et al. Proper cytoskeletal architecture beneath the plasma membrane of red blood cells requires Ttll4. Mol Biol Cell. 2017;28:535-544 pubmed publisher

product information

Catalog Number :

ABT185

Subcategory :

Cell Structure

Product Name :

Anti-Spectrin beta chain Antibody, erythrocyte

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P11277

Host Name :

Rabbit

Antigen :

Spectrin beta chain

Conjugate :

Affinity Purified

Product Description :

Anti-Spectrin beta chain Antibody, erythrocyte

Cross Reactivity :

Human;Mouse;Rat;Rhesus Macaque;Horse;Canine

Background :

Spectrin beta chain, erythrocyte (SPTB) is also known as Beta-I spectrin. Spectrin is the main member, along with band 4.1 and actin that form of the cytoskeletal framework underlying the erythrocyte plasma membrane. Spectrin is made up of nonhomologous chains, alpha and beta, which aggregate to form dimers, tetramers, and higher polymers. Defects in SPTB are the cause of elliptocytosis type 3 (EL3), as well as spherocytosis type 2 (SPH2) which are genetically heterogeneous, autosomal dominant hematologic disorders.

ALT Names :

Spectrin bet chain, erythrocyte;Beta-I spectrin

Immunogen :

KLH-conjugated linear peptide corresponding to the actin-binding of human Spectrin beta chain, erythrocyte

Specificity :

This antibody recognizes the Actin-binding domain of Spectrin beta chain, erythrocyte.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt