alpha Tubulin Antibody, tyrosinated | EMD Millipore ABT171 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

alpha Tubulin Antibody, tyrosinated

catalog :

ABT171

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, zebrafish

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - free floating section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; zebrafish ; 1:1000; fig 1	Jayachandran P, Olmo V, Sanchez S, McFarland R, Vital E, Werner J, et al. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016;11:1 pubmed publisher

product information

Catalog Number :

ABT171

Subcategory :

Cell Structure

Product Name :

Anti-alpha Tubulin Antibody, tyrosinated

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q71U36

Host Name :

Rabbit

Antigen :

alpha Tubulin

Conjugate :

Serum

Product Description :

Anti-alpha Tubulin Antibody, tyrosinated

Cross Reactivity :

Mouse;Monkey;Human;Rat

Background :

Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein which consists of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22 nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can be detyrosinated by a cytoskeleton associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation which is characteristic for microtubules in neuronal cells and the mitotic spindle.

ALT Names :

Tubulin alpha-1A chain;Alpha-tubulin 3;Tubulin B-alpha-1;Tubulin alpha-3 chain

Immunogen :

KLH-conjugated linear peptide corresponding to human tyrosinated alpha Tubulin.

Specificity :

This antibody detects the tyrosinated form of alpha Tubulin.

Package Size :

100 µL

Uses :

Western Blotting;ELISA;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.